News
Caprini Risk Assessment Tool Can Distinguish High Risk of VTE in Critically Ill Surgical Patients
December 1, 2015
Clinical question: Is the Caprini Risk Assessment Model for VTE risk valid in critically ill surgical patients? Background: Critically ill surgical patients are at increased risk of developing VTE. Chemoprophylaxis decreases VTE risk, but benefits must be balanced against bleeding risk.
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Adherence to Restrictive Red Blood Cell Transfusion Guidelines Improved with Peer Feedback
December 1, 2015
Clinical question: Can a multifaceted approach involving clinician education, peer email feedback, and monthly audit data improve adherence to restrictive red blood cell (RBC) transfusion guidelines? Background: Randomized controlled trials and professional society guidelines support adoption of
News
Corticosteroids Improve Outcomes in Community- Acquired Pneumonia
December 1, 2015
Clinical question: Are adjunctive corticosteroids beneficial for patients hospitalized with community-acquired pneumonia (CAP)? Background: Numerous studies have tried to determine whether or not adjunctive corticosteroids for CAP treatment in hospitalized patients improve outcomes.
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Standard Triple Therapy for H. Pylori Lowest Ranked among 14 Treatment Regimens
December 1, 2015
Clinical question: How do current Helicobacter pylori treatments compare in efficacy and tolerance? Background: Efficacy of standard “triple therapy” for H.
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Social Isolation, Polypharmacy Predict Medication Noncompliance Post-Discharge in Cardiac Patients
December 1, 2015
Clinical question: What are predictors of primary medication nonadherence after discharge? Background: Primary nonadherence occurs when a patient receives a prescription at hospital discharge but does not fill it.
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Inpatient Navigators Reduce Length of Stay without Increasing Readmissions
December 1, 2015
Clinical question: Does a patient navigator (PN) who facilitates communication between patients and providers impact hospital length of stay (LOS) and readmissions? Background: Increasing complexity of hospitalization challenges the safety of care transitions.
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News
Dexamethasone Potential Therapy for Asthma Exacerbations in Pediatric Inpatients
December 1, 2015
Clinical question: In children hospitalized in a non-ICU setting with asthma exacerbation, how effective is dexamethasone compared to prednisone/prednisolone? Background: Asthma is the second most common reason for hospital admission in childhood.1 National guidelines recommend treatment with sys
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Differences in Care, Outcomes for In-Hospital Versus Community-Onset Stroke
November 4, 2015
Clinical question: Are there any differences in care and outcomes for in-hospital versus community-onset stroke? Background: In-hospital stroke accounts for 4%-17% of all strokes. Hospitalists and other non-neurological services have to identify and treat subsequent stroke in their patients.
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Oral Steroids Not Inferior to Intravenous Steroids in Multiple Sclerosis Relapses
November 4, 2015
Clinical question: Is there any difference between oral and intravenous methylprednisolone for multiple sclerosis relapses? Background: When relapses of multiple sclerosis occur, studies have shown that intravenous steroids are the treatment of choice.
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Clinical Care Pathway for Cellulitis Can Help Reduce Antibiotic Use, Cost
November 4, 2015
Clinical question: How would an evidence-based clinical pathway for cellulitis affect process metrics, patient outcomes, and clinical cost? Background: Cellulitis is a common hospital problem, but its evaluation and treatment vary widely.
