Article
Lower Threshold Blood Pressure Associated with Reduced Postpartum ED Visits
September 3, 2025
Clinical question: Does tighter blood pressure (BP) control postpartum reduce emergency department (ED) visits for postpartum patients, and if yes, what are the cardiovascular risk...
Article
Early Thoracentesis Does Not Improve Clinical Outcomes in Acute HF
September 3, 2025
Clinical question: Does upfront thoracentesis improve short-term clinical outcomes for patients with acute heart failure (HF)? Background: Thoracentesis is being performed at increasing rates in...
Article
Albumin-Adjusted Calcium: Poorly Predictive, Yet Routinely Used
September 3, 2025
Clinical question: Is albumin-adjusted calcium a reliable surrogate for determining true calcium status, particularly when compared to ionized calcium, in adult patients? Background:...
Article
Pre-Treatment with IV Calcium Prior to IV Diltiazem Prevents Hypotension in AF
September 3, 2025
Clinical question: Can pre-treatment with IV calcium prevent hypotension in patients receiving IV diltiazem for atrial fibrillation (AF) or atrial flutter? Background: AF is the most commonly...
Article
Therapeutic-Dose Anticoagulation Shortened the Duration of ACS in Sickle Cell Disease Without Increasing Major Bleeding Risk
September 3, 2025
Clinical question: Does therapeutic-dose anticoagulation, compared to prophylactic dosing, improve clinical outcomes in adults with sickle cell disease hospitalized for acute chest syndrome...
Article
Hospital-Initiated MAUD: Oral and Extended-Release Naltrexone are Similarly Effective in Reducing Alcohol Use
September 3, 2025
Clinical question: Is there a difference in alcohol consumption between the oral and extended-release formulations of naltrexone when initiated in the hospital for patients with alcohol use disorder...
Article
Competencies for Those Who Coach Physicians: A Modified Delphi Study
September 3, 2025
Clinical question: What competencies are essential for coaching physicians effectively? Background: Physician coaching is founded on a supportive approach that empowers individuals and organizations...
Article
As-Needed BP Medication and Increased Adverse Outcomes in VA Hospitals
September 3, 2025
Clinical question: What are the adverse effects of as-needed BP medication on asymptomatic hypertension in hospitalized patients at risk of ischemic events due to high cardiovascular disease...
Article
Equivalent Mortality Regardless of Decision to Admit Versus Not to Admit in the 30 Days After an Index ED Visit
September 3, 2025
Clinical question: Do patients who are admitted to the hospital benefit from hospitalization, especially when the likelihood a given patient is admitted is highly dependent on the relative propensity...
Article
GPT-4 Assistance for Improvement of Physician Performance on Patient Care Tasks: A Randomized Controlled Trial
September 3, 2025
Clinical question: Does large language model (LLM) assistance improve physician performance on open-ended management reasoning tasks compared to conventional resources? Background: Management...