Article
Inpatient addiction-medicine consultation services decrease 90-day mortality and seven-day readmission rates, but not 30-day readmission rates or ED utilization
April 1, 2022
Dr. Munoa Clinical question: Do inpatient addiction-medicine consultation services (AMCS) affect patient mortality and medical utilization post-discharge? Background: AMCS are increasingly...
Article
Higher-than-expected recurrent VTE found in patients with isolated SSPE
April 1, 2022
Dr. Munoa Clinical question: What is the recurrence rate of venous thromboembolism (VTE) in patients with isolated subsegmental pulmonary embolisms (SSPE) managed without...
Article
Effectiveness of an analytics-based intervention for reducing sleep interruption in hospitalized patients
April 1, 2022
Dr. Scaletta Clinical question: Can a clinical-decision-support tool enable physicians to identify hospitalized patients who are stable enough to have their nighttime vital-sign checks...
Article
Safe to treat mild acute diverticulitis without antibiotics outside the hospital?
April 1, 2022
Dr. Scaletta Clinical question: Can clinicians successfully manage mild acute diverticulitis on an outpatient basis without antibiotics? Background: Incidence of diverticular disease is...
Article
No difference between balanced multi-electrolyte solution versus saline in critically ill adults
April 1, 2022
Dr. Knoeckle Clinical question: Does the use of a balanced multi-electrolyte solution (BMES) for fluid resuscitation in adults admitted to an intensive-care unit (ICU) impact 90-day...
Article
Efficacy of remdesivir in high-risk non-hospitalized patients
April 1, 2022
Dr. Taghvaei Clinical question: Does the use of remdesivir therapy in symptomatic, non-hospitalized, COVID-19 patients reduce disease progression and hospitalization? Background: Remdesivir...
Article
A proposed scoring system to assess COVID-19-induced coagulopathy and stratification of patients for anticoagulation therapy based on risk categories
February 3, 2022
Clinical question: Can a proposed new scoring system triage and assess risk in COVID-19 patients with coagulopathy? Dr. Ajala Background: COVID-19-induced coagulopathy (CIC), marked...
Article
Direct oral anticoagulants may be safe in cancer-related venous thromboembolisms, but use caution with gastrointestinal malignancies
February 3, 2022
Clinical question: Are direct oral anticoagulants (DOACs) a suitable alternative to low molecular weight heparin (LMWH) for treatment of venous thromboembolism (VTE) in patients with underlying...
Article
Breakthrough infection in COVID-19-vaccinated health care workers is associated with lower levels of neutralizing antibodies but less severe disease
February 3, 2022
Clinical question: How frequent are breakthrough infections in health care workers fully vaccinated against COVID-19, and how does vaccination correlate with immune response and infectivity? ...
Article
Aspirin increases the risk of clinically significant gastrointestinal bleeding in older persons
February 3, 2022
Clinical question: Does aspirin impact the risk of clinically significant gastrointestinal (GI) bleeding compared with placebo in community-dwelling older persons (aged >/= 70 years)? Dr....