Conference Coverage

Peanut is most prevalent culprit in anaphylaxis PICU admits


Key clinical point: Food is the most commonly identified cause of PICU admissions from anaphylaxis, with peanuts the main trigger among foods.

Major finding: Researchers found that 45% of these PICU stays from food were caused by reactions to peanuts.

Study details: A review of 1,989 cases during 2010-2015 in the Virtual Pediatrics Systems database, which collects international PICU information.

Disclosures: Dr. Davis reports financial relationships with Aimmune Therapeutics and DBV Technologies.

Source: Davis CM et al. 2018 AAAAI/WAO Joint Congress, Abstract 775.



– Food was found to be the most commonly identified trigger, with peanuts the most prevalent food cause, in what researchers say is the largest comprehensive review of anaphylaxis episodes in North America that led to pediatric intensive-care unit stays.

Researchers examined the Virtual Pediatrics Systems database, an international database of pediatric intensive care unit (PICU) information, said Carla M. Davis, MD, a pediatrician at Baylor College of Medicine, Houston. During 2010-2015, there were 1,989 pediatric anaphylaxis admissions to these units in North America, she reported at the joint congress of the American Academy of Allergy, Asthma and Immunology and the World Asthma Organization.

Dr. Carla M. Davis, a pediatrician at Baylor Medical School, Houston Thomas R. Collins/Frontline Medical Communications

Dr. Carla M. Davis

Dr. Davis said the study is intended to give a much-needed broad look at what is causing the most severe cases of child anaphylaxis.

“Because anaphylaxis is one of the most severe consequences of allergic disease, we decided that this study needed to be done to see really what the landscape was in the most critically ill children,” she said.

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