Article
Low-Dose Morphine as a Treatment for Chronic Breathlessness
June 1, 2026
Clinical question: Does low-dose, long-acting oral morphine improve self-reported breathlessness at 28 days for adult patients with moderate to severe chronic breathlessness? Background: Chronic...
Article
Optimal Timing of Anticoagulation Initiation After Ischemic Stroke in Patients with AF
April 6, 2026
CLINICAL QUESTION: In patients with atrial fibrillation (AF) and acute ischemic stroke, does early anticoagulation initiation (within four days) improve outcomes compared to delayed...
Article
Low-Dose Glucocorticoids Reduce Mortality in CAP
April 6, 2026
CLINICAL QUESTION: Do glucocorticoids reduce mortality in hospitalized adults with community-acquired pneumonia in a resource-limited setting? BACKGROUND: The use of glucocorticoids as adjunctive...
Article
Early TAVR Improved Outcomes for Elderly Patients with Asymptomatic Severe AS
March 2, 2026
CLINICAL QUESTION: In patients with asymptomatic severe aortic stenosis (AS) and preserved ejection fraction (EF), will early-intervention transcatheter aortic-valve replacement (TAVR), compared to...
Article
Navigational Bronchoscopy is Diagnostically Non-Inferior Compared to Transthoracic Needle Biopsy in Evaluation of Lung Nodules
February 2, 2026
CLINICAL QUESTION: In the evaluation of peripheral lung nodules, how does navigational bronchoscopy compare to transthoracic needle biopsy regarding diagnostic accuracy and procedural...
Article
Adding Budesonide to Albuterol Rescue Therapy in Patients with Mild Asthma Decreases Severe Exacerbations
February 2, 2026
CLINICAL QUESTION: Is as-needed albuterol-budesonide superior to albuterol alone in patients with mild asthma? BACKGROUND: Although patients with mild asthma are often considered low risk, they...
Article
Discordant Pleural Exudates Are Common and Have a Different Diagnostic Pattern Than Concordant Pleural Exudates
February 2, 2026
CLINICAL QUESTION: How common are discordant pleural fluid exudates, and do they have different diagnostic patterns compared to concordant pleural fluid exudates? BACKGROUND: Pleural effusions are...
Article
Dexamethasone Non-Inferior to Prednisone or Prednisolone for Treatment of Pediatric Asthma Exacerbations
January 5, 2026
CLINICAL QUESTION: How does dexamethasone compare to prednisone or prednisolone when used to treat pediatric asthma exacerbations? BACKGROUND: Historically, the standard of care steroid choice for...
Article
Nirsevimab Effectively Reduces RSV Infection and Hospitalizations
January 5, 2026
CLINICAL QUESTION: How effective is nirsevimab at preventing respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD), hospitalizations related to RSV, and any RSV...
Article
Lung POCUS: The Hospitalist’s New Stethoscope
July 31, 2025
In the time it takes to order, perform, and upload a stat chest X-ray, a skilled clinician with an ultrasound probe can diagnose an early pneumothorax, confirm pulmonary edema, or eyeball a...