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An Official Publication of
  • Clinical
    • In the Literature
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    • Interpreting Diagnostic Tests
    • Coding Corner
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In the Literature

  • Article

    Elevated fibrinogen and D-dimer relative to C-reactive protein linked to cognitive deficits post-COVID-19 hospitalization

    June 3, 2024

    Clinical question: Are acute blood biomarker profiles predictive of cognitive deficits following COVID-19 hospitalizations? Background: Cognitive deficits have been observed in many patients after...

  • Article

    Liberal transfusion strategy in acute myocardial infarction patients with anemia not shown to significantly reduce recurrent MI or death

    June 3, 2024

    Clinical question: What should be the transfusion target for patients hospitalized for myocardial infarction (MI) with anemia? Background: Data on the optimal transfusion target for patients with MI...

  • Article

    High-sensitivity versus conventional troponin in assessing PE risk

    June 3, 2024

    Clinical question: Is high-sensitivity cardiac troponin I (hs-cTnI) better at predicting outcomes for hemodynamically stable pulmonary embolism (PE) than conventional cardiac troponin I...

  • Article

    Limited utility in using NT-proBNP rather than functional capacity to estimate risk of perioperative MACE

    June 3, 2024

    Clinical question: Does adding N-terminal pro–B-type natriuretic peptide (NT-proBNP) to clinical risk scores provide a better estimate of the risk of major adverse cardiac events (MACE) among...

  • Article

    Semaglutide reduces major adverse cardiovascular events by 20% in patients with cardiovascular disease

    June 3, 2024

    Clinical question: Does semaglutide reduce cardiovascular events in non-diabetics with cardiovascular disease? Background: While glucagon-like peptide-1 (GLP-1) agonists reduce cardiovascular events...

  • Article

    Comparing in-hospital adverse events in elderly postoperative delirium patients: haloperidol versus atypical antipsychotics

    June 3, 2024

    Clinical question: Are in-hospital adverse events worse in post-operative delirium patients treated with haloperidol compared to atypical antipsychotics? Background: Post-operative delirium is...

  • Article

    Hydrocortisone reduces mortality in severe CAP

    June 3, 2024

    Clinical question: Does early hydrocortisone therapy reduce mortality among patients with severe community-acquired pneumonia (CAP) requiring admission to an intensive care unit (ICU) or intermediate...

  • Article

    Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF

    May 1, 2024

    Dr. Watson Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)? Background: Studies have shown an increased risk of...

  • Article

    High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF

    May 1, 2024

    Dr. Watson Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery,...

  • Article

    SGLT-2 inhibitors May Decrease Recurrent Gout Flares in Patients with Type 2 diabetes

    May 1, 2024

    Dr. Bernal Clinical question: Do SGLT-2 inhibitors decrease gout flares in patients with type 2 diabetes and a known history of gout? Background: Sodium–glucose cotransporter-2 inhibitors...

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