Article
Anticoagulation for AFib Increases Bleeding Risk and Death in Patients Over 65 with Cognitive Impairment
December 1, 2023
Clinical question: In older patients with atrial fibrillation (AFib), does frailty or cognitive function affect the risk of anticoagulation use? Dr. Enix Background: In older patients with...
Article
Administering Glucocorticoids Lowers Risk of Death in ICU Patients with Severe CAP
December 1, 2023
Clinical question: Does early administration of glucocorticoids to intensive care unit (ICU) patients with severe community-acquired pneumonia (CAP) reduce mortality? Ms. Harakal Background:...
Article
Gaps Remain in Hospital Discharge Education
December 1, 2023
Clinical question: What are medicine floor patients told about their hospital discharge instructions and by whom? Dr. Mutter Background studies: Prior studies have demonstrated suboptimal...
Article
Systemic Corticosteroids for Patients with Severe CAP
December 1, 2023
Clinical question: Among patients hospitalized with community-acquired pneumonia (CAP), does the addition of corticosteroids reduce mortality? Dr. Salline Background: Corticosteroids are used...
Article
Transcatheter Arterialization Provides Safe and Effective Treatment for No-option CLI
December 1, 2023
Clinical question: Is transcatheter arterialization of lower extremity deep veins safe and effective in preventing above-ankle amputation in patients with advanced chronic limb ischemia (CLI) who are...
Article
Direct Oral Challenge is Non-inferior to Skin Testing in Low-risk Penicillin Allergy Patients
October 2, 2023
Clinical question: Is there an alternative to penicillin skin testing for low-risk penicillin allergies? Dr. Miller Background: While approximately 10% of the population report...
Article
Deprescribing Medications Among Older Adults from the End of Hospitalization Through Post-acute Care
October 2, 2023
Clinical question: Can inpatient deprescribing interventions upon post-acute care facility discharge reduce the total medication burden? Dr. Kaur Background: Polypharmacy remains a common...
Article
Weighing Benefits and Risks of Indefinite Anticoagulation in First Unprovoked VTE
October 2, 2023
Clinical question: Is indefinite anticoagulation beneficial for patients with a first unprovoked venous thromboembolism (VTE) after initial treatment? Dr. Sheikh Background: VTE is a chronic,...
Article
Pitavastatin and Cardiovascular Disease Prevention in HIV Patients
October 2, 2023
Clinical question: Does pitavastatin reduce the risk of cardiovascular disease in human immunodeficiency virus (HIV)-infected individuals? Dr. Sheikh Background: Individuals with HIV infection...
Article
No Difference Between Liberal Versus Strict Perioperative BP Management in Non-cardiac Surgery
October 2, 2023
Clinical question: In patients on antihypertensive medications (AHMs) such as angiotensin-converting-enzyme inhibitors (ACE-Is) or angiotensin receptor blockers (ARBs) undergoing inpatient...