Article
Sodium-containing Acetaminophen Intake Increases the Risk of CVD and All-cause Mortality
October 3, 2022
Dr. Hoque Clinical question: Does the use of sodium-containing acetaminophen increase the risk of cardiovascular disease (CVD) and all-cause mortality in patients with and without a history of...
Article
CT Coronary Angiography in Stable Intermediate-risk Chest Pain
October 3, 2022
Dr. Mayer Clinical question: Is it safe to perform computed tomography (CT) coronary angiography to rule out obstructive coronary artery disease (CAD) in patients with stable intermediate-risk...
Article
Antiplatelet Medications and the Risk of ICH in Patients with Metastatic Brain Tumors
October 3, 2022
Dr. Vaidyan Clinical question: Do antiplatelet medications increase the risk of intracranial hemorrhage (ICH) in patients with metastatic brain tumors? Background: Brain metastases increase...
Article
There is a Decreased Risk of Hospitalization from Heart Failure in Type II Diabetics Initiated on a SGLT2 Inhibitor When Compared to a GLP-1 Receptor Agonist
September 1, 2022
Dr. Huang Clinical question: Determine the cardiovascular risk outcome in type II diabetic patients initiated on an sodium-glucose cotransporter-2 (SGLT2) inhibitor versus a glucagon-like...
Article
Transthoracic Echocardiography is Superior in Detecting Valvular Heart Disease
September 1, 2022
Ms. Nowak Clinical question: To quantify the extent to which undetectable heart sounds occur in hospitalized patients who are undergoing transthoracic echocardiography and evaluate the...
Article
Acute Care for the Elderly in the Home Environment Increased Physical Activity Levels While Lowering Costs, Health Care Use, and Readmissions
September 1, 2022
Dr. Nagaraj Clinical question: Can hospital-level care be provided in the home environment to reduce costs without compromising the quality of care in the U.S.? Background: Inpatient care is...
Article
Mirtazapine is Not an Effective Treatment for Agitation in Dementia
September 1, 2022
Ms. Whalen CLINICAL QUESTION: What’s the clinical effectiveness and safety profile of mirtazapine in reducing agitation in dementia relative to placebo? BACKGROUND: Nonpharmacological...
Article
Oral Antibiotics and a Combination Regimen of IV and Oral Antibiotics for Treatment of Acute Uncomplicated Appendicitis Yielded Similar Success Rates
September 1, 2022
Dr. Andleeb Clinical question: Are oral antibiotics effective and non-inferior to a combination of intravenous and oral antibiotics? Background: Evidence over the past 10 years suggests that...
Article
Low-dose Rivaroxaban at Discharge Prevented Some VTE Events at One Month for High-risk Patients Recovering from COVID-19
September 1, 2022
Dr. Thazhatuveetil-Kunhahamed Clinical Question: Is extended rivaroxaban prophylaxis (10 mg daily for 35 days) protective against arterial and venous thromboembolism (VTE) events in COVID-19...
Article
The risk for intestinal necrosis with SPS is very low
August 1, 2022
Dr. Lippert Clinical question: What is the risk of intestinal necrosis with sodium polystyrene (SPS) for the treatment of hyperkalemia? Background: SPS is a medication that has been available...