Article
Is 7 Really the Magic Number for RBC Transfusion?
May 1, 2024
Over the past decade, there has been widespread adoption of restrictive red blood cell (RBC) transfusion guidelines.1,2 As a result, RBC transfusions have significantly decreased per...
Article
Can Pentoxifylline Improve Healing of Lower Extremity Ulcers?
May 1, 2024
Case The patient, Mr. D, has been experiencing swelling in his legs for several years, and seven months prior, he noticed that his skin had started to develop ulcers. He has class 3 obesity, type 2...
Article
Use of Amiodarone with Apixaban or Rivaroxaban Increases Risk for Bleeding-related Hospitalizations
March 1, 2024
Clinical question: Does the use of amiodarone in patients with atrial fibrillation increase the risk for bleeding-related hospitalizations when used with apixaban or rivaroxaban? Background:...
Article
ODS in Hospitalized Patients with Hyponatremia
September 1, 2023
Dr. Mohoney Clinical question: Of the patients who are admitted with hyponatremia, how many develop osmotic demyelination syndrome (ODS)? Background: ODS is a rare but serious complication...
Article
Consider Platelet Transfusion Prior to CVC Placement for Patients with High-risk Thrombocytopenia
September 1, 2023
Dr. Meyer Clinical question: Can central venous catheters (CVC) be safely placed in patients with platelet counts less than 50,000 without administration of platelets prior to the...
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News
Anticoagulant choice in antiphospholipid syndrome–associated thrombosis
December 10, 2021
Are direct oral anticoagulants (DOACs) as efficacious and safe as vitamin K antagonists (VKAs) in treating thrombosis secondary to antiphospholipid syndrome (APS)?
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News
Apixaban a reasonable alternative to warfarin in patients with severe renal impairment
December 9, 2021
Is apixaban a safe alternative to warfarin in patients with severe renal impairment?
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News
Apixaban outmatches rivaroxaban for VTE in study
December 6, 2021
These real-world findings may guide selection of initial anticoagulant therapy, according to authors of the paper.
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News
Apixaban noninferior to low-molecular-weight heparin in cancer-associated VTE
December 6, 2021
Is oral apixaban as safe and effective as subcutaneous dalteparin in treating venous thromboembolism (VTE) in patients with underlying cancer?
News
Rituximab likely raises risk of hospital death in COVID-19 patients
December 2, 2021
In a retrospective study of hospitalized COVID-19 patients, “only 1 of 303 drugs examined, rituximab, was associated with an increased risk of in-hospital death ... both when used for rheumatologic as well as for cancer therapy.”
