Article
Use of Amiodarone with Apixaban or Rivaroxaban Increases Risk for Bleeding-related Hospitalizations
March 1, 2024
Clinical question: Does the use of amiodarone in patients with atrial fibrillation increase the risk for bleeding-related hospitalizations when used with apixaban or rivaroxaban? Background:...
Article
ODS in Hospitalized Patients with Hyponatremia
September 1, 2023
Dr. Mohoney Clinical question: Of the patients who are admitted with hyponatremia, how many develop osmotic demyelination syndrome (ODS)? Background: ODS is a rare but serious complication...
Article
Consider Platelet Transfusion Prior to CVC Placement for Patients with High-risk Thrombocytopenia
September 1, 2023
Dr. Meyer Clinical question: Can central venous catheters (CVC) be safely placed in patients with platelet counts less than 50,000 without administration of platelets prior to the...
News
Anticoagulant choice in antiphospholipid syndrome–associated thrombosis
December 10, 2021
Are direct oral anticoagulants (DOACs) as efficacious and safe as vitamin K antagonists (VKAs) in treating thrombosis secondary to antiphospholipid syndrome (APS)?
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Apixaban a reasonable alternative to warfarin in patients with severe renal impairment
December 9, 2021
Is apixaban a safe alternative to warfarin in patients with severe renal impairment?
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Apixaban outmatches rivaroxaban for VTE in study
December 6, 2021
These real-world findings may guide selection of initial anticoagulant therapy, according to authors of the paper.
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Apixaban noninferior to low-molecular-weight heparin in cancer-associated VTE
December 6, 2021
Is oral apixaban as safe and effective as subcutaneous dalteparin in treating venous thromboembolism (VTE) in patients with underlying cancer?
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Rituximab likely raises risk of hospital death in COVID-19 patients
December 2, 2021
In a retrospective study of hospitalized COVID-19 patients, “only 1 of 303 drugs examined, rituximab, was associated with an increased risk of in-hospital death ... both when used for rheumatologic as well as for cancer therapy.”
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Tranexamic acid does not reduce risk of death in GI bleed
December 2, 2021
In patients with GI bleeding, does high-dose tranexamic acid (TXA) reduce the risk of death?
News
Oakland score identifies patients with lower GI bleed at low risk for adverse events
November 23, 2021
Is the Oakland score a valid tool to assess the risk of adverse outcomes in adult patients with acute lower GI bleed (LGIB)?