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Hematology (blood)

  • Article

    Antibiotic Treatment for 7 days is Noninferior to 14 days in Patients with Uncomplicated Bacteremia

    June 2, 2025

    Clinical question: Is seven days of antibiotic treatment for bloodstream infections noninferior to 14 days of treatment? Background: Bloodstream infections are very common, can originate from a...

  • Article

    Restrictive Transfusion in MI May Lead to an Increase in 6-Month Mortality

    June 2, 2025

    Clinical question: How does a restrictive transfusion strategy (transfusion threshold of 7 to 8 g/dL) compare to a liberal transfusion strategy (transfusion threshold of 10 g/dL) in patients with...

  • Article

    Should Hospitalists Throw Caution to the Wind? Overly Cautious Correction of Severe Hyponatremia May Lead to Greater Harm Than Good

    June 2, 2025

    Clinical question: Does the correction rate for hospitalized adults with severe hyponatremia correlate with mortality or length of stay?  Background: Hyponatremia is a commonly encountered problem...

  • Article

    Gram-Negative Bacteremia: Early Transition from IV to PO Antibiotic Therapy

    March 4, 2025

    Clinical question: What is the safety and efficacy of switching from IV to oral antibiotic therapy after three to five days in patients with gram-negative bacteremia? Background: Bacteremia is...

  • Article

    Slower Correction of Sodium in Severe Hyponatremia is Associated with Increased Mortality and Length of Stay

    March 4, 2025

    Clinical question: Is the sodium correction rate in severe hyponatremia associated with mortality and length of stay? Background: Hyponatremia is commonly encountered in the hospital, with high...

  • Article

    Interpretation of Serum Ammonia Level

    December 2, 2024

    A 77-year-old woman with a history of hepatitis C cirrhosis presents to the emergency department with 24 hours of progressive confusion and disorientation. The physical exam is notable for...

  • Article

    When Should I Transfuse My Adult Hospitalized Patient Who Has Anemia?

    December 2, 2024

    Update to the 2017 article When should I transfuse a patient who has anemia?  Case An 82-year-old woman with chronic lymphocytic leukemia complicated by anemia of chronic disease (baseline...

  • Article

    Challenging Anticoagulation Scenarios: How to Have Smooth Sailing through Choppy Waters

    July 1, 2024

    Keeping abreast of updates in anticoagulation guidelines is important for physicians to provide optimal patient care. Multiple changes to recommendations for anticoagulation have been made in the...

  • Article

    Solving Major Problems: Major Bleeding and Major Surgery for Patients on Anticoagulants

    July 1, 2024

    This interactive session posed real-life scenarios for hospitalists who frequently deal with difficult anticoagulation questions and grounded it all with the evidence. The first case discussed was...

  • Article

    Is 7 Really the Magic Number for RBC Transfusion?

    May 1, 2024

      Over the past decade, there has been widespread adoption of restrictive red blood cell (RBC) transfusion guidelines.1,2 As a result, RBC transfusions have significantly decreased per...

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