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Anticoagulant choice in antiphospholipid syndrome–associated thrombosis
December 10, 2021
Are direct oral anticoagulants (DOACs) as efficacious and safe as vitamin K antagonists (VKAs) in treating thrombosis secondary to antiphospholipid syndrome (APS)?
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Apixaban a reasonable alternative to warfarin in patients with severe renal impairment
December 9, 2021
Is apixaban a safe alternative to warfarin in patients with severe renal impairment?
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Apixaban outmatches rivaroxaban for VTE in study
December 6, 2021
These real-world findings may guide selection of initial anticoagulant therapy, according to authors of the paper.
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Apixaban noninferior to low-molecular-weight heparin in cancer-associated VTE
December 6, 2021
Is oral apixaban as safe and effective as subcutaneous dalteparin in treating venous thromboembolism (VTE) in patients with underlying cancer?
News
Rituximab likely raises risk of hospital death in COVID-19 patients
December 2, 2021
In a retrospective study of hospitalized COVID-19 patients, “only 1 of 303 drugs examined, rituximab, was associated with an increased risk of in-hospital death ... both when used for rheumatologic as well as for cancer therapy.”
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Tranexamic acid does not reduce risk of death in GI bleed
December 2, 2021
In patients with GI bleeding, does high-dose tranexamic acid (TXA) reduce the risk of death?
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Oakland score identifies patients with lower GI bleed at low risk for adverse events
November 23, 2021
Is the Oakland score a valid tool to assess the risk of adverse outcomes in adult patients with acute lower GI bleed (LGIB)?
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Timing of endoscopy for acute upper GI bleeding
November 18, 2021
In high-risk patients hospitalized with upper GI bleeding, is earlier endoscopy beneficial?
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Ticagrelor reversal agent achieves quick hemostasis: REVERSE-IT
November 17, 2021
The monoclonal antibody bentracimab, which can rapidly reverse ticagrelor, was found effective and safe in an FDA-requested interim analysis of a phase 3 trial.
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Autopsy findings reveal venous thromboembolism in patients with COVID-19
October 12, 2021
What pathologic features contribute to the cause of death in COVID-19?
