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Clinical Guidelines

  • Self-identified black patients experience higher rates of occult hypoxemia

    May 2, 2022

    Dr. Long Clinical question: Are there disparities in hypoxemia detection by pulse oximetry across self-identified racial groups and, if so, is there an association with clinical...

  • Article

    Interpretation of the Urine Drug Screen

    May 2, 2022

    Dr. Cunningham Case A 40-year-old male with depression, post-traumatic stress disorder, and chronic pain presents with somnolence and a respiratory rate of 10 breaths per minute that responded to...

  • Article

    Negative initial CSF studies in HSV encephalitis portend worse neurologic outcomes

    May 2, 2022

    Clinical question: Does delay in diagnosis of herpes simplex virus (HSV) encephalitis due to negative initial cerebrospinal fluid (CSF) studies affect neurologic outcomes? Dr....

  • Article

    No difference between balanced multi-electrolyte solution versus saline in critically ill adults

    April 1, 2022

    Dr. Knoeckle Clinical question: Does the use of a balanced multi-electrolyte solution (BMES) for fluid resuscitation in adults admitted to an intensive-care unit (ICU) impact 90-day...

  • Article

    To treat or not to treat: interpreting syphilis serologies

    February 3, 2022

    Case A 32-year-old man with history of intravenous heroin use presents to the emergency department (ED) for fevers and redness with purulence over the left forearm. He is started on IV vancomycin...

  • News

    D-dimer thresholds rule out PE in meta-analysis

    December 14, 2021

    Data from a large review support use of D-dimer levels to diagnose PE without imaging.

  • 1
    News

    Timing of initiation of renal-replacement therapy in acute kidney injury

    December 8, 2021

    In critically ill patients, does early renal-replacement therapy (RRT), compared with standard therapy, improve death from any cause at 90 days?

  • News

    Predicting cardiac shock mortality in the ICU

    November 23, 2021

    Including biventricular dysfunction as assessed using transthoracic echocardiography improves clinical risk stratification.

  • 1
    News

    Timing of renal-replacement therapy for AKI in the ICU

    November 19, 2021

    Does earlier initiation of renal-replacement therapy (RRT) improve mortality in the ICU?

  • News

    Faster testing possible for secondary ICU infections

    November 18, 2021

    Researchers have shown the potential for clinical metagenomics to become a same-day test for identifying secondary infection in ventilated ICU patients.

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