Article
Detectable MNPs in Carotid Artery Plaques Are Associated with a Higher Risk of Myocardial Infarction, Stroke, or Death
December 2, 2024
Clinical question: Do patients with carotid artery plaque containing detectable microplastics and nanoplastics (MNPs) have a higher risk of myocardial infarction, stroke, or death? Background:...
Article
Improving HF Outcomes in Obesity and Type 2 Diabetes: The Role of Semaglutide
December 2, 2024
Clinical question: Does semaglutide improve heart failure (HF) symptoms in patients with obesity-related HF and type 2 diabetes? Background: Obesity-related HF and type 2 diabetes are prevalent...
Article
Acute Cardiac Events are Common Among Adults 50 Years or Older Hospitalized with RSV and Associated with Severe Disease
December 2, 2024
Clinical question: How common are acute cardiac events among hospitalized older adults (50 years or older) with respiratory syncytial virus (RSV) infection and what are the associated risk...
Article
Early Versus Later Anticoagulation for Stroke with Atrial Fibrillation
October 1, 2024
Mr. Gegg-Mitchell Clinical question: What is the safety and efficacy of early compared with later initiation of direct oral anticoagulants (DOACs) in patients with atrial fibrillation and...
Article
The STRONG-HF Trial: Evaluating the Safety, Tolerability, and Effectiveness of Up-titrating GDMT in Acute Heart Failure
August 1, 2024
Clinical question: Does rapid up-titration of guideline-directed medical therapies (GDMT) following admission for acute heart failure improve patient outcomes? Background: GDMT provides...
Article
Ticagrelor or Prasugrel in Patients with Acute Coronary Syndromes
August 1, 2024
Clinical question: Is the treatment strategy with ticagrelor superior to prasugrel in acute coronary syndrome (ACS) with planned invasive evaluation at one year? Background: Dual antiplatelet...
Article
Syncope: Things We Do for No Reason & Things We Do for Reason
July 1, 2024
Syncope is broadly classified into reflex-mediated (60% to 70%), orthostatic (10%), and cardiac (10% to 20%). Cerebrovascular causes were removed from American and European guidelines (or listed as a...
Article
Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF
May 1, 2024
Dr. Watson Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)? Background: Studies have shown an increased risk of...
Article
High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF
May 1, 2024
Dr. Watson Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery,...
Article
Semaglutide in Patients with HFpEF and Obesity
May 1, 2024
Dr. Cepeda Mora Clinical question: Is semaglutide an effective heart failure treatment in patients with heart failure with preserved ejection fraction (HFpEF) and obesity? Background: HFpEF is...