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In the Literature

  • News

    Modified IV Acetylcysteine Infusion Reduces Adverse Effects

    October 27, 2014

    Clinical question: Does a shorter regimen of IV acetylcysteine reduce adverse effects compared to the standard regimen? Background: Acetaminophen poisoning is common, and recommended treatment is IV acetylcysteine; however, the standard regimen has many adverse effects, including vomiting and ana

  • News

    No Mortality Benefit with Treatment of Single Peripheral Pulmonary Emboli

    October 27, 2014

    Clinical question: Does treatment of single peripheral pulmonary emboli impact mortality and rates of post-discharge venous thromboembolism (VTE)? Background: With the increase in CT pulmonary angiography (CTPA) use the past decade, there has been an increased rate of detection of peripheral fill

  • News

    Healthcare-Associated Infections Continue to Impact the U.S. Healthcare System Financially

    October 27, 2014

    Clinical question: What is the estimated cost of healthcare-associated infections (HAI) to the U.S. healthcare system? Background: In spite of education efforts, HAIs occur frequently and contribute to high healthcare costs in the U.S. This study sought to estimate the costs of HAIs to the U.S.

  • 1
    News

    Short Course of Oral Antibiotics Effective for Acute Osteomyelitis and Septic Arthritis in Children

    October 27, 2014

    By Mark Shen, MD Reviewed by Pediatric Editor Mark Shen, MD, medical director of hospital medicine at Dell Children’s Medical Center, Austin, Texas. Clinical question: Is a short course (less than four weeks) of antibiotics effective for the treatment of acute osteomyelitis and septic arthritis?

  • News

    Once-Weekly Antibiotic Might Be Effective for Treatment of Acute Bacterial Skin Infections

    October 15, 2014

    Research suggests intravenous dalbavancin similarly efficacious to intravenous vancomycin

  • News

    Continuous Positive Airway Pressure Outperforms Noctural Oxygen for Blood Pressure Reduction

    October 15, 2014

    CPAP better at decreasing 24-hour mean arterial pressure in patients with obstructive sleep apnea, coronary artery disease, cardiac risk factors

  • News

    Lactate Clearance Portends Better Outcomes after Cardiac Arrest

    October 13, 2014

    Lower lactate levels, greater clearance associated with better survival, neurological outcomes

  • News

    Time to Meds Matters for Patients with Cardiac Arrest Due to Nonshockable Rhythms

    October 13, 2014

    Earlier administration of epinephrine associated with better survival outcomes

  • News

    Frailty Indices Tool Predicts Post-Operative Complications, Mortality after Elective Surgery in Geriatric Patients

    October 13, 2014

    Tool uses pre-operative comprehensive geriatric assessment that includes fraily measurement

  • News

    Pre-Operative Use of Angiotension Converting Enzyme Inhibitors, Angiotension Receptor Blockers Examined in Elective Joint Replacement Surgery

    October 13, 2014

    ACEI/ARB administration associated with higher risk of intra-operative hypotension, acute kidney injury

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