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In the Literature

  • News

    Pre-Operative Beta Blockers May Benefit Some Cardiac Patients

    October 27, 2014

    Clinical question: In patients with ischemic heart disease (IHD) undergoing non-cardiac surgery, do pre-operative beta blockers reduce post-operative major cardiovascular events (MACE) or mortality at 30 days? Background: Peri-operative beta blocker use has become more restricted, as evidence abo

  • News

    Facecards Improve Familiarity with Physician Names but Not Satisfaction

    October 27, 2014

    Clinical question: Do facecards improve patients’ familiarity with physicians and increase satisfaction, trust, and agreement with physicians? Background: Facecards can improve patients’ knowledge of names and roles of physicians, but their impact on other outcomes is unclear.

  • News

    New Oral Anticoagulants Safe and Effective for Atrial Fibrillation Treatment

    October 27, 2014

    Clinical question: Is there a difference in efficacy and safety among new oral anticoagulants compared to warfarin in subgroups of patients with atrial fibrillation (Afib)? Background: Studies of new oral anticoagulants have demonstrated that these agents are at least as safe and effective as war

  • News

    Sepsis Diagnoses Are Common in ED, but Many Septic Patients in the ED Do Not Receive Antibiotics

    October 27, 2014

    Clinical question: Has the frequency of sepsis rates, along with administration of antibiotics in U.S.

  • News

    Multifaceted Discharge Interventions Reduce Rates of Pediatric Readmission and Post-Hospital ED Utilization

    October 27, 2014

    Clinical question: Do interventions at discharge reduce the rate of readmissions and post-hospitalization ED visits among pediatric patients? Background: Readmissions are a high-priority quality measure in both the adult and pediatric settings.

  • News

    Warfarin Initiation in Atrial Fibrillation Associated with Increased Short-Term Risk of Stroke

    October 27, 2014

    Clinical question: Is the initiation of warfarin associated with an increased risk of ischemic stroke in patients with atrial fibrillation (Afib)? Background: Two Afib trials of oral factor Xa inhibitors showed an increased risk of stroke when patients were transitioned to open label warfarin at

  • 1
    News

    Variation in the Treatment of Henoch-Schönlein Purpura

    October 27, 2014

    Reviewed by Pediatric Editor Mark Shen, MD, medical director of hospital medicine at Dell Children’s Medical Center, Austin, Texas. Clinical question: What is the degree of variation in the inpatient management of Henoch-Schönlein purpura (HSP)? Background: HSP is the most common pediatric vascu

  • News

    Comorbidities Contribute to Potentially Avoidable Hospital Readmissions

    October 27, 2014

    Clinical question: What is the role of comorbidities in 30-day potentially avoidable readmissions? Background: Higher comorbidity burden has been associated with 30-day readmissions.

  • News

    Uncomplicated Skin Infections in Ambulatory Setting Commonly Involve Avoidable Antibiotic Exposure

    October 27, 2014

    Clinical question: What are the current prescribing practices for antibiotics used to treat skin and soft tissue infections in the outpatient setting? Background: Uncomplicated skin and soft tissue infections are among the most frequent indications for outpatient antibiotic use.

  • News

    Resident Handoff Bundle Reduces Medical Errors and Adverse Events, Improves Handoff Quality

    October 27, 2014

    Clinical question: In a pediatric inpatient setting, is the use of a handoff program associated with improved patient safety measures and handoff quality? Background: Sentinel events related to errors in communication are a significant patient safety dilemma and an impetus for ongoing efforts to

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