News
Effects of Peri-Operative Beta-Blockade in Noncardiac Surgery Vary Based on Cardiac Risk Factors
September 9, 2015
Research Review: Peri-Operative Beta-Blockade in Noncardiac Surgery
News
Risk for In-Hospital Adverse Cardiac Events Low for Some Patients with Chest Pain
September 9, 2015
Clinical question: Do stable, low-risk patients hospitalized for chest pain after negative ED evaluation experience adverse cardiac events in the hospital? Background: Chest pain results in more than seven million ED visits annually, with a cost of over $11 billion to hospitalize these patients f
News
New Strategy in Patients with Suspected Heparin-Induced Thrombocytopenia Improves Diagnostic Accuracy
September 9, 2015
Clinical question: Can a diagnostic strategy that utilizes a clinical prediction rule combined with an immunoassay appropriately guide management for patients with suspected heparin-induced thrombocytopenia (HIT)? Background: The appropriate and timely diagnosis of HIT can decrease the risks of t
News
Vasoactive Medications Safe in ICU via Peripheral Intravenous Access
September 9, 2015
Clinical question: Can vasoactive medications be safely given in the ICU via peripheral intravenous (PIV) access instead of central venous access? Background: Vasoactive medications are given to a variety of patients in shock to maintain hemodynamic function.
News
Cost, Frequency of Emergency Department Revisits Evaluated
September 9, 2015
Clinical question: What is the cost and frequency of ED revisits within three days and 30 days? Background: ED revisits lead to a financial and resource utilization burden on the medical system.
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Early, Late Hospital Readmission Factors Differ
September 9, 2015
Clinical question: What are the differences between factors associated with early (zero to seven days after discharge) and late (eight to 30 days after discharge) readmission? Background: Thirty-day readmission rates are a quality metric; however, recent evidence challenges the notion that readmi
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Patient Adherence to Pharmacological Thromboprophylaxis Improves with Interventions
September 9, 2015
Clinical question: How can patient adherence to pharmacological thromboprophylaxis be improved? Background: Prior studies suggest that the hospital-wide prevalence of nonadministration of VTE thromboprophylaxis orders ranges from 5% to 13%, with patient refusal listed as the most common reason fo
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Mortality Risk in Patients Older than 75 Presenting with Non-ST-Elevation Acute Coronary Syndrome
September 9, 2015
Clinical question: Is there a score that will predict the mortality rate in elderly patients presenting with a non-ST-elevation myocardial infarction (NSTEMI)? Background: Although they represent only 9% of patients in clinical trials, patients over the age of 75 make up one third of patients wit
News
Clinical Variables Predict Debridement Failure in Septic Arthritis
July 29, 2015
Clinical question: What risk factors predict septic arthritis surgical debridement failure? Background: Standard treatment of septic arthritis is debridement and antibiotics. Unfortunately, 23%-48% of patients fail single debridement.
News
Prednisolone or Pentoxifylline Show No Mortality Benefit in Alcoholic Hepatitis
July 29, 2015
Clinical question: Does administration of prednisolone or pentoxifylline reduce mortality in patients hospitalized with severe alcoholic hepatitis? Background: Alcoholic hepatitis is associated with high mortality.