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Clinical

  • News

    Post-Operative Transfusions after Noncardiac Surgery Associated with Increased Adverse Outcomes

    October 29, 2015

    Clinical question: Do transfusions affect post-operative outcomes after noncardiac surgery? Background: Studies have demonstrated that a restrictive transfusion strategy is probably superior to a liberal transfusion strategy in many clinical settings.

  • News

    Easing the Grieving Process for Families of Patients Dying in the ICU

    October 29, 2015

    Clinical question: Can we dignify death in the ICU and ease the grieving process by soliciting wishes from patients, families, and care team members? Background: The death of the critically ill patient in the ICU can be dehumanizing and overwhelming for the patient’s family and friends, leading t

  • 1
    News

    Pediatric Trigger Tool Helps Identify Inpatient Pediatric Harm

    October 29, 2015

    Clinical question: Can a trigger tool identify harms for hospitalized children? Background: An estimated 400,000 people die annually in the United States as a result of hospital-associated harm.

  • News

    Left Atrial Appendage Closure Favorable Over Warfarin for Atrial Fibrillation

    October 29, 2015

    Clinical question: Is there a favorable risk-benefit ratio for left atrial appendage closure (LAAC) compared to warfarin for prevention of stroke, systemic embolism, and cardiovascular death in nonvalvular atrial fibrillation? Background: LAAC with the WATCHMAN device was shown to be noninferior

  • News

    Thrombosis Management Demands Delicate, Balanced Approach

    October 22, 2015

    The delicate balance involved in providing hospitalized patients with needed anticoagulant, anti-platelet, and thrombolytic therapies for stroke and possible cardiac complications while minimizing bleed risks was explored by several speakers at the University of California San Francisco’s annual Man

  • 1
    News

    “Wish List” Outlines Patients’ Expectations for Hospital Stays, and Some Easy Fixes

    October 20, 2015

    Even before HCAHPS (Hospital Consumer Assessment of Healthcare Providers and Systems), hospital leaders and clinicians were striving to provide not only high quality care, but a place patients choose to meet their future healthcare needs.

  • 1
    News

    Urinalysis Is Reliable Infection Predictor in Infants

    October 6, 2015

    Clinical question: In infants younger than three months of age with bacteremic urinary tract infection (UTI), how sensitive and specific are urinalysis (UA) findings? Background: Infants are commonly hospitalized with UTIs. The gold standard for diagnosis is considered to be urine culture.

  • News

    High-Flow Nasal Oxygen Therapy Noninferior to BiPAP in Post-Operative Respiratory Failure

    October 6, 2015

    Clinical question: In post-operative cardiothoracic surgery patients, is high-flow nasal oxygen therapy inferior to BiPAP for resolution of acute respiratory failure? Background: Acute respiratory failure is common following cardiothoracic surgery, and noninvasive ventilation often is used to avo

  • News

    Supplemental Oxygen During STEMI Might Increase Myocardial Injury

    October 6, 2015

    Clinical question: Does routine oxygen supplementation in patients with STEMI increase myocardial injury? Background: Because of physiologic and clinical studies conducted before the era of acute coronary intervention, supplemental oxygen routinely is administered to patients with STEMI, regardle

  • News

    Thrombectomy Within Eight Hours of Stroke Onset Reduces Post-Stroke Disability

    October 6, 2015

    Clinical question: Does thrombectomy, in conjunction with medical therapy, improve functional independence in patients with an acute proximal anterior stroke? Background: Revascularization of proximal anterior strokes with alteplase alone occurs less than 50% of the time.

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