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    News

    Enhancing Mobility Reduces Length of Stay

    June 3, 2016

    Clinical question: Can a nurse-driven early ambulation program aimed at all hospitalized adults increase patient mobility and decrease length of stay? Background: Many adults experience decline of functional abilities during their hospitalization.

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    News

    Can Sepsis Be Better Defined?

    June 3, 2016

    Clinical question: Given advances in the understanding and treatment of sepsis, can sepsis be better defined? Background: Definitions of sepsis and septic shock were last revised in 2001.

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    News

    Disinfection Caps Reduce CLABSI, BCC in Hematology-Oncology Patients

    May 30, 2016

    Clinical question: Does the use of disinfection caps on catheter hubs on central venous catheters (CVCs) reduce central-line-associated bloodstream infection (CLABSI) and blood culture contamination (BCC) in hematology-oncology patients? Background: CVCs have facilitated the administration of che

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    News

    Isopropyl Alcohol Nasal Inhalation Effective Treatment for ED Nausea

    May 30, 2016

    Clinical question: Does inhaled isopropyl alcohol alleviate nausea as compared to inhaled saline solution among patients presenting to the ED with a chief complaint of nausea? Background: Nausea and vomiting account for 4.8 million ED visits each year; however, antiemetics have not shown superior

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    News

    Chronic Kidney Disease Risk with Proton Pump Inhibitors

    May 27, 2016

    Clinical question: What is the association between proton pump inhibitor (PPI) use and incident chronic kidney disease (CKD)? Background: Medication use may play a potential role in the increasing prevalence of CKD.

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    News

    Risk Factors for Pseudomonas, MRSA in Healthcare-Associated Pneumonia

    May 27, 2016

    Clinical question: What risk factors could predict the likelihood of Pseudomonas and methicillin-resistant Staphylococcus aureus (MRSA) in patients hospitalized with healthcare-associated pneumonia (HCAP)? Background: Patients identified with HCAP have an increased risk for multi-drug-resistant p

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    News

    Updated CHEST Guidelines for Antithrombotic Therapy of VTE

    May 23, 2016

    Clinical question: What are the current recommendations for antithrombotic therapy in various venous thromboembolism (VTE) scenarios? Background: VTE is commonly encountered with a multitude of therapeutic options.

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    News

    Tamsulosin Can Be Used as Expulsive Therapy for Some Ureteric Stones

    May 23, 2016

    Clinical question: Is tamsulosin efficacious as an expulsive therapy for distal ureter stones ≤10 mm in diameter? Background: Ureteric calculi are a common reason for hospital admission, and use of medical expulsive therapy during observation periods for small caliber stones has gained much atten

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    News

    Prevalence, Characteristics of Physicians Prone to Malpractice Claims

    May 20, 2016

    Clinical question: Do claim-prone physicians account for a substantial share of all paid malpractice claims? Background: Many studies have compared physicians who have multiple malpractice claims against them with colleagues who have few or no claims against them and have identified systemic diff

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    News

    Association of Frailty on One-Year Postoperative Mortality Following Major Elective Non-Cardiac Surgery

    May 20, 2016

    Clinical question: What is the association of preoperative frailty on one-year postoperative mortality? Background: Frailty is an aggregate expression of susceptibility to poor outcomes owing to age and disease-related deficits that accumulate with multiple domains.