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Clinical

  • Article

    Statins should be continued in hospitalized patients with COVID-19

    May 2, 2022

    Clinical question: Does discontinuation of atorvastatin in those hospitalized with COVID-19 change the risk of mortality and ventilation? Dr. Clark Background: Statins are ubiquitous. Statins...

  • Article

    Non-gastrointestinal complications, including ischemic stroke, are more common than bleeding or perforation following screening colonoscopy in older adults

    May 2, 2022

    Clinical question: What serious non-gastrointestinal adverse events are due to screening colonoscopy? Dr. Gordon Background: Although the gastrointestinal (GI) risks of colonoscopy have been...

  • Article

    Health care systems can do more to support environmental health services employees

    May 2, 2022

    Clinical question: What has been the experience of environmental services (EVS) employees working during the COVID-19 pandemic? Dr. Gordon Background: EVS employees play an essential role in...

  • Article

    Apixaban plus a P2Y12 inhibitor best balances bleeding and ischemic events in patients with atrial fibrillation and recent acute coronary syndrome or percutaneous coronary intervention

    May 2, 2022

    Clinical question: Can the HAS-BLED and CHA2DS2-VASc scores be used to identify subgroups of patients with atrial fibrillation (AF) and recent acute coronary syndrome (ACS) or percutaneous coronary...

  • Article

    CPAP reduces the risk of intubation among patients with acute hypoxemic respiratory failure and COVID-19

    May 2, 2022

    Clinical question: What is the role of continuous positive airway pressure (CPAP) and high-flow nasal oxygen (HFNO) compared to conventional oxygen therapy in the management of COVID-19-related acute...

  • Article

    A structured end-of-life communication strategy reduces prolonged grief in families of dying ICU patients

    May 2, 2022

    Clinical question: Does a proactive, three-step, support strategy decrease prolonged grief in relatives of patients who die in the intensive care unit (ICU)?  Dr. Wood Background: Prolonged...

  • Article

    Midline catheters may be safer than PICCs

    April 1, 2022

    Dr. Indovina Clinical question: Are midline catheters safer than peripherally inserted central catheters (PICCs)?  Background: The use of midline catheters instead of PICCs has grown, but...

  • Article

    Consider post-discharge VTE prophylaxis for COVID-19 patients

    April 1, 2022

    Dr. Indovina Clinical question: Should extended post-discharge venous thromboembolism (VTE) prophylaxis be prescribed for patients with COVID-19? Background: While VTE prophylaxis during...

  • Article

    Ultrasound JVP measurement accurately predicts right atrial pressure

    April 1, 2022

    Dr. Cunningham Clinical question: Does measurement of ultrasound jugular venous pressure (JVP) height by ultrasound (uJVP) in the semi-upright position accurately predict right atrial pressure...

  • Article

    Improved cardiovascular outcomes with CABG compared to FFR-guided PCI in patients with three-vessel CAD

    April 1, 2022

    Dr. Cunningham Clinical question: How does fractional flow reserve (FFR)-guided percutaneous intervention (PCI) with second-generation drug-eluting stents compare with coronary artery bypass...

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