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De-Escalate Antibiotics for Community-Onset Sepsis After Four Days
March 31, 2012
Clinical question: Is de-escalation of broad-spectrum antibiotics (BSAs) safe on encounter day four in patients with community-onset sepsis with no positive tests for multidrug-resistant organisms...
Dalbavancin Non-Inferior, But Not Superior, to Standard Therapy for Treatment of Complicated Staphylococcus aureus Bacteremia
March 31, 2012
CLINICAL QUESTION: Among patients with complicated Staphylococcus aureus bacteremia who achieve blood culture clearance with initial therapy, is completion of treatment with dalbavancin superior to...
FMT is a Noninferior Treatment Option for Primary CDI
March 31, 2012
CLINICAL QUESTION: Is fecal microbiota transplantation (FMT) safe and efficacious in the treatment of primary Clostridioides difficile infection (CDI)? BACKGROUND: FMT is currently recommended for...
Comparing Screening Tools for Predicting Sepsis Among Children
March 31, 2012
CLINICAL QUESTION: Which screening tool performs best for early prediction of sepsis and septic shock in children per the Phoenix criteria? BACKGROUND: Early recognition of sepsis remains...