Secondary endpoints were the need for revascularization and cranial-nerve palsy at one year. During the first month after procedure, 4.8% of patients in the stent group and 9.8% of patients in the surgical group reached the primary endpoint. In the subsequent year, 12.2% of stent patients and 20.1% of surgical patients reached the primary endpoint (absolute risk reduction of 7.9, CI 0.7-16.4 and NNT 14). Cranial nerve palsy at one year was 0% vs. 4.9% in the stent vs. surgical group. Need for revascularization at one year was 0.6% vs. 4.3% for stent vs. surgical group. Although this study was designed to show the non-inferiority of angioplasty vs. carotid endarterectomy in patients deemed suitable for either procedure, it actually was statistically significant for superiority of stenting. It also implied a lower complication rate in terms of cranial nerve palsy and the need for revascularization at one year.
Related Articles
How Do You Ethically Integrate a GIP Hospice Service into the Hospital?
January 2, 2005
Case An 86-year-old female with a history of metastatic pancreatic cancer and diabetes was admitted for chest pain and dyspnea and found to have an acute pulmonary embolism. The hospital...
Strategies for Dysfunctional Teams and Groups
January 2, 2005
Drs. Russo and Boer began by outlining the differences between high-performing and dysfunctional teams. High-performing teams are not afraid of face-to-face communication, authentically give and...
Syncope Evaluation: Evidence-Based and Economical
January 2, 2005
Dr. Daniel Dressler started his evidence-based evaluation of the syncope presentation by polling the audience with a few cases and questions regarding syncope. Before finding out the correct answers,...
Investing in the Future
January 2, 2005
Q & A with Raman Palabindala, MD, MBA, SFHM, CLHM, regional medical director of population health, Optum, Seattle, Wash. Dr. Palabindala, a volunteer member of The Hospitalist's editorial...