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An Official Publication of
  • Clinical
    • In the Literature
    • Key Clinical Questions
    • Interpreting Diagnostic Tests
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Dennis Chang, MD

  • News

    D-Dimer Not Reliable Marker to Stop Anticoagulation Therapy

    May 5, 2015

    Clinical question: In patients with a first unprovoked VTE, is it safe to use a normalized D-dimer test to stop anticoagulation therapy? Background: The risk of VTE recurrence after stopping anticoagulation is higher in patients who have elevated D-dimer levels after treatment.

  • News

    Noninvasive Ventilation Improves Outcomes for COPD Inpatients

    May 5, 2015

    Clinical question: Do patients hospitalized with acute COPD exacerbations have improved outcomes with noninvasive ventilation (NIV) compared to those treated with invasive mechanical ventilation (IMV)? Background: Previous studies have shown that in select patients, NIV has a mortality benefit ov

  • News

    Bova Risk Model Predicts 30-Day Pulmonary Embolism-Related Complications

    May 5, 2015

    Clinical question: Can the Bova risk model stratify patients with acute PE into stages of increasing risk for 30-day pulmonary embolism (PE)-related complications? Background: The Bova score is based on four variables assessed at the time of PE diagnosis: heart rate, systolic blood pressure, card

  • News

    Intracranial Bleeding Risk for Head Injury Patients on Warfarin

    May 5, 2015

    High bleeding rates reported for patients taking warfarin after minor, minimal head injuries

  • News

    Enriched Nutritional Formulas Help Heal Pressure Ulcers

    May 5, 2015

    Arginine, zinc, antioxidant-supplemented formulas improve healing in malnourished patients

  • News

    High-Volume Hospitals Have Higher Readmission Rates

    May 5, 2015

    Clinical question: Is there an association between hospital volume and hospital readmission rates? Background: There is an established association between high patient volume and reduced complications or mortality after surgical procedures; however, readmission represents a different type of qual

  • News

    Hospital Testing Overuse Done to Reassure Patients, Families

    May 5, 2015

    Clinical Question: What is the extent of, and factors associated with, testing overuse in U.S.

  • News

    Functional Impairment Boosts Readmission for Medicare Seniors

    May 5, 2015

    Clinical question: Is functional impairment associated with an increased risk of 30-day readmission? Background: Many Medicare seniors suffer from some level of impairment in functional status, which, in turn, has been linked to high healthcare utilization.

  • News

    Delirium, Falls Reduced by Nonpharmacological Intervention

    May 5, 2015

    Clinical question: Are multicomponent, nonpharmacological interventions effective in decreasing delirium and falls? Background: Delirium is prevalent among elderly hospitalized patients and is associated with increased morbidity, length of stay, healthcare costs, and risk of institutionalization.

  • News

    Bridging Anticoagulation for Patients with Atrial Fibrillation

    May 5, 2015

    Bridging prior to procedures linked with higher bleeding risk, adverse outcomes

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