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News
Dapagliflozin benefits low-EF heart failure regardless of diuretic dose: DAPA-HF
June 26, 2020
The trial that turned an SGLT2 inhibitor into a heart failure drug also has clues to mechanisms behind the observed benefits. Contrary to early speculation, diuresis may be off the list.
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DAPA-HF: Dapagliflozin slows T2D onset in heart failure patients
June 16, 2020
In the landmark DAPA-HF trial that enrolled HFrEF patients without diabetes, treatment with dapagliflozin cut incident type 2 diabetes by a relative 32%.
News
FDA okays emergency use for Impella RP in COVID-19 right heart failure
June 2, 2020
The authorization allows use of the temporary heart pump in the treatment of right heart failure or decompensation, including pulmonary embolism, caused by COVID-19 complications.
News
FDA approves dapagliflozin for low-EF heart failure
May 7, 2020
The approval based on DAPA-HF makes dapagliflozin (Farxiga) the only drug in its class to be indicated for heart failure in the absence of diabetes.
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Tools for preventing heart failure
February 13, 2020
SNOWMASS, COLO. – “There will be more than 1 million new cases of heart failure this year, and the vast majority of them could have been prevented.” – Gregg C. Fonarow, MD
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Treatment of heart failure with preserved ejection fraction is a work in progress
January 13, 2020
Although the disorder has a lower mortality than heart failure with reduced ejection fraction, it places a significant burden on health care systems.
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New heart failure trial data presage guideline revisions
December 9, 2019
PHILADELPHIA – Recent trial findings for sacubitril/valsartan and dapagliflozin in heart failure patients provide a blueprint for guideline changes.
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News
FDA adds diabetic kidney disease, heart failure indications to canagliflozin
September 30, 2019
This marks the first time in 20 years that a drug has been indicated for diabetic kidney disease treatment, according to the manufacturer.
News
Machine learning–derived risk score predicts heart failure risk in diabetes patients
September 22, 2019
Highest WATCH-DM scores linked to 5-year heart failure risk approaching 20%.
News
Drug doses for heart failure could possibly be halved for women
September 12, 2019
Women reached the highest level of drug efficacy at half the doses of ACE inhibitors or ARBs and beta-blockers needed by men to reach the same level.