AstraZeneca COVID vaccine: Clotting disorder mechanism revealed?
April 2, 2021
The vaccine may be linked to a condition that clinically resembles heparin-induced thrombocytopenia and seems to occur mainly in younger women.
DOACs offered after heart valve surgery despite absence of data
March 9, 2021
Use of direct oral anticoagulants following heart valve surgery is occurring despite relative contraindications, but expert doubts its clinical significance.
Late-window stroke thrombolysis not linked to clot migration
March 3, 2021
This is the first randomized controlled study to assess the effect of thrombolysis on clot migration and accessibility in an extended time window.
Microthrombi, necrosis seen in COVID-19 hearts on autopsy
February 3, 2021
A new autopsy series shows microthrombi and focal necrosis in hearts of patients who died of COVID-19. The findings support use of anticoagulation, but best dosing remains unclear, researchers say.
DAPT increases bleeding without decreasing mortality in patients with coronary disease and diabetes
February 2, 2021
In patients who have diabetes with known coronary disease but without prior MI or stroke, what is the effect of dual-antiplatelet therapy (DAPT) with aspirin and ticagrelor on cardiovascular outcomes and bleeding events?
Anticoagulation and antiplatelet therapy after GI bleed cut mortality, ischemic events
January 28, 2021
In patients who present with a gastrointestinal bleed (GIB) while on an anticoagulants (AC) or antiplatelets (AP), what are the risks and benefits to resuming these medications?
Full-dose anticoagulation reduces need for life support in COVID-19
January 25, 2021
“We have treatments that are improving outcomes but not as many that reduce mortality, so we’re hopeful when the full dataset comes in that will be confirmed.”
DOACs show safety benefit in early stages of CKD
January 15, 2021
In terms of efficacy and bleeding risk, what is known about anticoagulation in patients with chronically impaired renal function?
A standardized approach to postop management of DOACs in AFib
January 13, 2021
Is it safe to adopt a standardized approach to direct oral anticoagulant (DOAC) interruption for patients with atrial fibrillation (AFib) who are undergoing elective surgeries/procedures?
In COVID-19 patients, risk of bleeding rivals risk of thromboembolism
January 12, 2021
Trials are urgently needed to define optimal anticoagulation strategies for COVID-19 infection.