News
Anticoagulation Therapy Probably Not Needed While A-fib Patients Undergo Surgery
June 23, 2015
NEW YORK (Reuters Health) - When patients with atrialfibrillation need surgery or other invasive therapy, doctors can safely interrupt their warfarin therapy without offering a bridging anticoagulation regimen, according to a new U.S.-Canadian study. The test of 1,884 patients treated
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Increased VTE Prophylaxis Shows Little Benefit following Colorectal Surgery
June 18, 2015
NEW YORK—Although venous thromboembolism (VTE) rates are low in hospitalized patients following colorectal surgery, the increasing use of prophylaxis seems to have little impact, according to Washington state-based researchers. Dr. Scott R.
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Peri-Operative Phlebotomy Might Cause Significant Blood Loss in Cardiac Surgery Patients
June 8, 2015
Clinical question: What are the frequency of laboratory testing, the average total blood volume drawn per patient, and the resulting transfusion utilization in patients undergoing cardiac surgery? Background: Healthcare providers seldom recognize the amount of phlebotomy, and, therefore, its cons
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Restrictive Transfusion Strategy No Benefit for Cardiac Surgery Patients
May 4, 2015
Clinical question: Does a restrictive transfusion strategy improve outcomes following nonemergent cardiac surgery? Bottom line: For patients undergoing cardiac surgery, using a restrictive transfusion strategy with a hemoglobin threshold of 7.5 g/dL does not decrease serious infections or ischemi
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Aspirin vs. Anticoagulation for VTE Prevention in Lower Extremity Orthopedic Surgery
January 7, 2015
Clinical question: What are rates of venous thromboembolism (VTE) and bleeding among adult patients receiving aspirin versus anticoagulants after major lower extremity orthopedic surgery? Background: VTE is common after hip fracture surgery and elective total knee/hip arthroplasty.
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Colchicine Prevents Postpericardiotomy Syndrome Following Cardiac Surgery
November 10, 2014
Clinical question Does perioperative colchicine reduce postpericardiotomy syndrome following cardiac surgery? Bottom line The use of colchicine in the perioperative period decreases the incidence of postpericardiotomy syndrome after cardiac surgery with a number needed to treat (NNT) of 10.
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Fluvastatin Improves Postoperative Cardiac Outcomes in Patients Undergoing Vascular Surgery
October 29, 2014
Clinical question: Does perioperative fluvastatin decrease adverse cardiac events after vascular surgery? Background: Patients with atherosclerotic vascular disease who undergo vascular surgery are at high risk for postoperative cardiac events.
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High Perioperative Oxygen Fraction Does Not Improve Surgical-Site Infection Frequency after Abdominal Surgery
October 27, 2014
Clinical question: Does the use of 80% oxygen perioperatively in abdominal surgery decrease the frequency of surgical-site infection within 14 days without increasing the rate of pulmonary complications? Background: Low oxygen tension in wounds can negatively impact immune response and healing.
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Frailty Indices Tool Predicts Post-Operative Complications, Mortality after Elective Surgery in Geriatric Patients
October 13, 2014
Tool uses pre-operative comprehensive geriatric assessment that includes fraily measurement
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Pre-Operative Use of Angiotension Converting Enzyme Inhibitors, Angiotension Receptor Blockers Examined in Elective Joint Replacement Surgery
October 13, 2014
ACEI/ARB administration associated with higher risk of intra-operative hypotension, acute kidney injury