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Pulmonology

  • Article

    High-Flow Nasal Cannula Versus Non-Invasive Ventilation for AECOPD

    April 1, 2025

    Clinical question: Is high-flow nasal cannula oxygen therapy (HFNC) non-inferior to non-invasive ventilation (NIV) for acute exacerbations of chronic obstructive pulmonary disease (AECOPD) in...

  • Article

    The CONVINCE Trial: No Reduction in Recurrent Vascular Events with Long-Term Colchicine Use After Ischemic Stroke

    April 1, 2025

    Clinical question: Does long-term colchicine use plus guideline-based care after ischemic stroke prevent recurrent vascular events? Background: According to the World Health Organization, stroke is...

  • Article

    Gabapentinoid Use Associated with Increased Risk of Severe Exacerbations in Patientswith COPD

    March 4, 2025

    Clinical question: Does gabapentinoid use increase the risk of severe exacerbation in patients with chronic obstructive pulmonary disease (COPD)? Background: Gabapentinoids are indicated for the...

  • Article

    Inhaled Amikacin in the First 72 Hours of Mechanical Ventilation Reduced the Incidence of VAP

    January 1, 2025

    Clinical question: Does inhaled amikacin reduce the incidence of ventilator-associated pneumonia (VAP) in critically ill patients? Background: VAP is a common and serious complication in patients on...

  • Article

    Clinical Risk Score Predicts Arterial Thrombosis in Survivors of Intracranial Hemorrhage

    January 1, 2025

    Clinical question: Among survivors of hemorrhagic stroke, who is at high long-term risk of arterial thrombosis? Background: Patients who survive intracerebral hemorrhage (ICH) are at increased risk...

  • Article

    Acute Cardiac Events are Common Among Adults 50 Years or Older Hospitalized with RSV and Associated with Severe Disease

    December 2, 2024

    Clinical question: How common are acute cardiac events among hospitalized older adults (50 years or older) with respiratory syncytial virus (RSV) infection and what are the associated risk...

  • Article

    Gabapentinoids and Risk for Severe Exacerbation in COPD

    December 2, 2024

    Clinical question: Is gabapentinoid use associated with severe exacerbation in patients with chronic obstructive pulmonary disease (COPD)? Background: The U.S. Food and Drug Administration issued a...

  • Article

    Coding Corner: Spoonful of Sugar

    October 1, 2024

    A 46-year-old woman is admitted to the hospital with an exacerbation of chronic obstructive pulmonary disease (COPD) requiring intensification of her inhaler regimen, initiation of corticosteroids,...

  • Article

    Comparing Outcomes of Targeted Reperfusion Therapy Versus Anticoagulation in Patients with Acute Intermediate-high-risk PE

    October 1, 2024

    Ms. Jang Clinical question: Do patients with acute intermediate-high-risk pulmonary embolism (PE) benefit more in terms of cardiac function from reperfusion therapy with conventional...

  • Article

    DAPT Versus Alteplase for Patients With Minor Non-disabling Acute Ischemic Stroke

    April 1, 2024

    Clinical question: Is dual antiplatelet therapy (DAPT) non-inferior to intravenous thrombolysis in patients with minor non-disabling acute ischemic stroke? Background: Intravenous thrombolytics are...

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