Article
Comparing Screening Tools for Predicting Sepsis Among Children
January 5, 2026
CLINICAL QUESTION: Which screening tool performs best for early prediction of sepsis and septic shock in children per the Phoenix criteria? BACKGROUND: Early recognition of sepsis remains...
Article
Significant Pathology in Young Infants Presenting with Hypothermia: A Multicenter Study
January 5, 2026
CLINICAL QUESTION: Among infants aged 90 days or younger who present to the emergency department (ED) or hospital with hypothermia, what is the prevalence of significant pathology, and what pathology...
Article
Pediatric Nurses Provide Unique Perspectives on PFC Rounds
January 5, 2026
CLINICAL QUESTION: What are the benefits and barriers to participating in patient-and-family-centered (PFC) rounds from a pediatric nursing perspective? BACKGROUND: Interprofessional PFC rounding...
Article
BRUE Prediction Rules Outperform the AAP Higher-Risk Criteria in Estimating Risk for Serious Underlying Diagnosis
January 5, 2026
CLINICAL QUESTION: Do the recently derived clinical prediction rules for brief resolved unexplained events (BRUE) perform better than the American Academy of Pediatrics (AAP) higher-risk criteria in...
Article
Dexamethasone Non-Inferior to Prednisone or Prednisolone for Treatment of Pediatric Asthma Exacerbations
January 5, 2026
CLINICAL QUESTION: How does dexamethasone compare to prednisone or prednisolone when used to treat pediatric asthma exacerbations? BACKGROUND: Historically, the standard of care steroid choice for...
Article
Pediatric Catatonia’s Medical Turn: Increasing Incidence and Intensifying Treatment
January 5, 2026
CLINICAL QUESTION: Has the incidence, etiology, evaluation, and management of pediatric catatonia changed over time, especially following the COVID-19 pandemic? BACKGROUND: Pediatric catatonia is a...
Article
Nirsevimab Effectively Reduces RSV Infection and Hospitalizations
January 5, 2026
CLINICAL QUESTION: How effective is nirsevimab at preventing respiratory syncytial virus (RSV) lower respiratory tract disease (LRTD), hospitalizations related to RSV, and any RSV...
Article
Limited Diagnostic Yield from Specialty Consultation and Testing Following BRUE
January 5, 2026
CLINICAL QUESTION: Among infants who experience brief resolved unexplained events (BRUE) (irrespective of their American Academy of Pediatrics risk stratification), how often do specialty...
Article
Less May Be More: Rethinking Antibiotic Use in Tracheostomized Children
January 5, 2026
CLINICAL QUESTION: Among hospitalized children with tracheostomies who develop respiratory symptoms (tracheobronchitis and nonspecific respiratory episodes), what is the pattern of antibiotic use,...
Article
A Quality Improvement Initiative Significantly Improves Critical-Care Billing on a Pediatric Hospital Medicine Service
January 5, 2026
CLINICAL QUESTION: How can pediatric hospitalists improve critical-care billing and documentation for hospitalized pediatric patients? BACKGROUND: Appropriate billing significantly impacts hospital...