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Nephrology (kidneys)

  • Stewardship Prompts to Improve Antibiotic Selection for UTI

    May 1, 2025

    Clinical question: Can computerized provider order entry (CPOE) prompts reduce the use of empiric extended-spectrum antibiotics in patients with urinary tract infections (UTI)? Background: UTIs...

  • Article

    Effects of Semaglutide on CKD in Patients with Type 2 Diabetes: the FLOW Trial

    April 1, 2025

    Clinical question: Does treatment with semaglutide in patients with type 2 diabetes and chronic kidney disease (CKD) prevent the progression of CKD or death from kidney and cardiovascular...

  • Article

    Renal Function and Decongestion with ADHF: the ADVOR Trial

    March 4, 2025

    Clinical question: Does acetazolamide enhance loop diuretic effect in patients with acute decompensated heart failure (ADHF) and how does this combination affect renal function? Background: Nearly...

  • Article

    Semaglutide Decreases Risk of Kidney Failure, Worsening of Kidney Disease, and Kidney-Related or Cardiovascular Death

    March 4, 2025

    Clinical question: Does treatment with semaglutide in patients with chronic kidney disease (CKD) and diabetes mellitus (DM) type II reduce the risk of kidney failure, progression of chronic kidney...

  • Article

    Metronidazole-Related Encephalopathy and Neuropathy Associated with IV Administration, Liver Cirrhosis, and CKD

    January 1, 2025

    Clinical question: What is the prevalence of metronidazole-related neurologic adverse events and what are the risk factors associated with these events? Background: A 2021 study reported neurologic...

  • Article

    Incidence of Colorectal Cancer in Patients Diagnosed with PLA

    November 1, 2024

    Dr. Katsnelson Clinical question: Is there an association between pyogenic liver abscess (PLA) and subsequent incidence of diagnosed colorectal cancer (CRC) and if so, should early screening for...

  • Article

    To RAASi or Not to RAASi, That is the Question

    October 1, 2024

    Clinical question: Should angiotensin-converting enzyme inhibitors (ACEi) or angiotensin receptor blockers (ARBs) be discontinued or continued in advanced chronic kidney disease (CKD)...

  • Article

    ACLF Grade 3 Predicts Risk of Respiratory Failure with Terlipressin Use

    October 1, 2024

    Ms. Boyle Clinical question: Which risk factors predict new-onset respiratory failure during terlipressin use for the treatment of patients with rapidly deteriorating kidney function attributed...

  • Article

    IV Sodium Thiosulphate for Calciphylaxis of CKD: A Systematic Review and Meta-analysis

    August 1, 2024

    Clinical question: Does IV sodium thiosulphate improve skin lesions and survival in patients with chronic kidney disease (CKD) experiencing calciphylaxis? Background: Calciphylaxis, also called...

  • Article

    DOACs Versus Warfarin Across the Spectrum of Kidney Function

    April 1, 2024

    Clinical question: How safe are direct oral anticoagulants (DOACs) to use in kidney dysfunction? Background: DOACs are increasingly being used in patients with kidney dysfunction. DOACs are cleared,...

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