News
Avoid Trimethoprim-Sulfamethoxazole for Severe MRSA Infections
July 9, 2015
Clinical question: Is trimethoprim-sulfamethoxazole equivalent to vancomycin for the treatment of severe infections caused by methicillin-resistant Staphyloccus aureus? Bottom line: Trimethoprim-sulfamethoxazole (TMP-SMX) did not achieve noninferiority as compared with vancomycin for the treatmen
![1]()
News
Childhood Bacteremia and Antibiotics Usage in the Emergency Department
July 6, 2015
How vaccination against pneumococcus has changed microbiology of pediatric bacteremia
News
Patient Complexities Associated With Antibiotic Ordering
July 6, 2015
Research Review: Patient Complexities and Antibiotic Ordering
News
Revised Guideline for Adult Bacterial Meningitis Improves Treatment, Outcome
July 6, 2015
Clinical question: Did revision of guidelines recommending computerized tomography (CT) scan before lumbar puncture (LP) reduce delayed treatment of acute bacterial meningitis (ABM)? Background: Guidelines were introduced in Sweden in 2004 identifying patients at risk for LP-induced brain herniat
News
Precaution Guidelines Updated for Visitors of Inpatients with Infectious Diseases
May 29, 2015
Hospitalists may soon see changes in precaution protocols for some hospital visitors, thanks to a revised set of guidelines published by the Society for Healthcare Epidemiology of America (SHEA).
News
Antibiotic Regimens Compared for Treating Uncomplicated Skin Infections
May 19, 2015
Clinical question: What are the efficacy and safety of clindamycin and trimethoprim-sulfamethoxazole (TMP-SMX) for treatment of uncomplicated soft tissue infections in adults and children? Background: Clindamycin and TMP-SMX are commonly used treatments for uncomplicated skin infections
![1]()
News
Children with Acute Hematogenous Osteomyelitis Have Similar Outcomes When Discharged with Oral Antibiotics versus Prolonged IV Antibiotics and Escape PICC Complications
March 3, 2015
Clinical question: After hospitalization for acute hematogenous osteomyelitis (AHOM), do children discharged with oral antibiotics have similar clinical outcomes compared to those discharged with home IV antibiotics? Background: AHOM occurs in one in 5,000 children yearly and makes up approximate
News
Infectious Diseases Society of America 2014 Practice Guidelines To Diagnose, Manage Skin, Soft Tissue Infections
March 3, 2015
Background Surveillance studies in the U.S.
News
Procalcitonin-Based Algorithm Does Not Reduce Antibiotic Use in the ICU
February 10, 2015
Clinical question Can a procalcitonin-based algorithm reduce antibiotic use in critically ill patients? Bottom line A procalcitonin-based algorithm using a 0.1 ng/mL cutoff does not significantly decrease the duration of antibiotic treatment in critically ill patients nor does it reduce length
News
Antibiotic Therapy Guidelines for Pediatric Pneumonia Helpful, Not Hurtful
December 19, 2014
Hospitalists need not fear negative consequences when prescribing guideline-recommended antibiotic therapy for children hospitalized with community-acquired pneumonia (CAP), according to a recent study conducted at Cincinnati Children’s Hospital Medical Center (CCHMC). "Guideline-recommended ther
