Article
Comparing Screening Tools for Predicting Sepsis Among Children
January 5, 2026
CLINICAL QUESTION: Which screening tool performs best for early prediction of sepsis and septic shock in children per the Phoenix criteria? BACKGROUND: Early recognition of sepsis remains...
Article
Significant Pathology in Young Infants Presenting with Hypothermia: A Multicenter Study
January 5, 2026
CLINICAL QUESTION: Among infants aged 90 days or younger who present to the emergency department (ED) or hospital with hypothermia, what is the prevalence of significant pathology, and what pathology...
To Treat or Not to Treat? Mycoplasma and Its Controversies
November 5, 2025
PHM 2025 Session Recap In a unique session at PHM 2025, an intensivist, a hospitalist, and two infectious disease specialists provided an update on Mycoplasma pneumoniae from the lens of their...
Treating Influenza: Yay or Nay to Antivirals?
October 1, 2025
Vote Yay for Treating Flu A (Dr. Mehta) We, as a nation, recently experienced an influenza epidemic that was the worst in 15 years in my state of Ohio. Questions reminiscent of the pre-pandemic...
Article
The Pneumonia Playbook: Updates for Hospitalists
July 1, 2025
Several clinical scenarios were reviewed by Maria E. Theodorou, MD, FACP, FHM, an associate professor at Northwestern University Feinberg School of Medicine in Chicago, highlighting the clinical...
Article
Updates in Sepsis
July 1, 2025
The annual sepsis update, delivered by Meshell Johnson, MD, ATSF, professor of medicine at the University of California in San Francisco, distilled a year’s worth of high-impact evidence into...
Article
Efficacy of Adjuvant Corticosteroid Therapy for CAP Varied Significantly Based on C-Reactive Protein Concentrations
June 2, 2025
Clinical question: Can baseline C-reactive protein concentrations help identify which patients with community-acquired pneumonia (CAP) are most likely to benefit from adjuvant treatment with...
Article
Continuous Versus Intermittent Infusion of β-Lactam Antibiotics in Critically Ill Patients with Sepsis
May 1, 2025
Clinical question: Does continuous infusion of β-lactam antibiotics reduce 90-day mortality compared with intermittent infusion in critically ill patients with sepsis? Background: Sepsis, a...
Article
90-Day Mortality Among Septic Patients Given Piperacillin-Tazobactam Versus Cefepime
January 1, 2025
Clinical question: In patients with undifferentiated sepsis without an indication for anaerobic coverage, is there increased mortality with the combined use of vancomycin/piperacillin-tazobactam...
Article
Hydrocortisone Plus Fludrocortisone for CAP-Related Septic Shock
January 1, 2025
Clinical question: Does hydrocortisone and fludrocortisone reduce all-cause mortality among patients with septic shock due to community-acquired pneumonia (CAP)? Background: A meta-analysis of 17...