Article
Bolus IV 0.9% Saline Leads to Interstitial Permeability Pulmonary Edema in Healthy Volunteers
March 1, 2023
Clinical question: Can intravenous fluid (IVF) administration cause direct lung injury independent of cardiogenic overload? Background: Bolus IVF therapy is a central component to managing...
Article
Effectiveness of Oxycodone Hydrochloride vs. Combination Acetaminophen and Codeine for Subacute Pain After Fractures Managed Surgically: A Randomized Controlled Trial
March 1, 2023
Clinical question: Do less potent opioids suffice for adequate pain control for patients with surgically managed fractures? Background: For post-surgical pain management at time of discharge,...
Article
Nutritional Support Improves Mortality in Frail, Elderly Patients
March 1, 2023
Clinical question: Is there a mortality benefit to optimizing nutritional status for malnourished patients with age-related frailty? Background: Age-related frailty syndrome has been associated with...
Article
Mirtazapine Administration Associated with Moderate Risk of Hyponatremia
March 1, 2023
Clinical question: What is the incidence of hyponatremia in patients treated with mirtazapine? Background: The development of hyponatremia has been associated with selective serotonin inhibitors and...
Article
Aggressive IV Fluids Plus Rectal NSAIDs Don’t Prevent Post-ERCP Pancreatitis
January 3, 2023
Dr. Moulder Clinical question: Does the addition of aggressive intravenous hydration to rectal nonsteroidal anti-inflammatory drugs (NSAIDs) help prevent post-endoscopic retrograde...
Article
Syncopal Event Doesn’t Necessarily Mean Driving Restriction
January 3, 2023
Dr. Young Clinical question: Do patients with first syncopal events suffer more motor vehicle collisions (MVCs) than patients without syncope? Background: Recommendations for driving...
Article
Legionella Risk Model Guides Appropriate Testing
January 3, 2023
Dr. Crane Clinical question: Can select patient demographic data and risk factors help predict Legionella infection better than clinical gestalt or current Infectious Diseases Society of America...
Article
Initiation of Empagliflozin in Hospitalized Patients with Acute Decompensated HF Improves Clinical and Symptomatic Outcomes at 90 Days
January 3, 2023
Dr. Kerley Clinical question: Does initiation of empagliflozin in hospitalized patients with acute decompensated heart failure improve clinical outcomes and symptom burden? Background: Studies...
Article
Issues Related to Testing are the Most Common Source of Diagnostic Errors in Primary Care
January 3, 2023
Dr. Dreicer Clinical question: How can we categorize diagnostic pitfalls leading to diagnostic errors in primary care? Background: Diagnostic errors are a leading cause of malpractice claims and...
Article
Rivaroxaban Monotherapy is Preferable to Combination Therapy with Antiplatelets with Regards to Total Cardiovascular and Bleeding Events in Patients with AF and Stable CAD
January 3, 2023
Dr. Clemo Clinical question: Is there a difference in total thrombotic and/or bleeding events in patients with atrial fibrillation (AF) and stable coronary artery disease (CAD) on rivaroxaban...