Article
Abatacept and Infliximab May Improve Mortality in Patients Hospitalized with COVID-19 Pneumonia
February 1, 2024
Dr. Rose Clinical question: What immunomodulatory drugs should we use in hospitalized patients with COVID-19 in addition to corticosteroids? Background: Inflammation is a key driver of morbidity...
Article
Risk Stratification of Patients with HF in the ED Coupled with Close Outpatient Follow-up Reduces Mortality and CV Rehospitalization
February 1, 2024
Dr. Latifi Clinical question: In patients presenting to the emergency department (ED) with heart failure (HF) symptoms, are patient outcomes affected by the use of a risk stratification tool to...
Article
Risk for CKD Progression After AKI
February 1, 2024
Dr. Dalal Clinical question: Is acute kidney injury (AKI) associated with subsequent worsening of renal function trajectory in patients with chronic kidney disease (CKD)? Background: Prior...
Article
Partial Oral Antibiotic Therapy May be Effective in Treating Complicated MRSA Among People with IDU
December 1, 2023
Clinical question: Are oral antibiotics effective in completing treatment for complicated methicillin-resistant Staphylococcus aureus (MRSA) among patients with injection drug use (IDU)? Dr....
Article
Cellulitis is Frequently Misdiagnosed
December 1, 2023
Clinical question: How accurate is the initial diagnosis of cellulitis in adult patients compared to subsequent specialist consultation? Dr. Lessing Background: Diagnosis of cellulitis leads...
PE Presents in 1/3 of Patients with Recent Onset of Exertional Dyspnea
December 1, 2023
Clinical question: What is the prevalence of pulmonary embolism (PE) among emergency department (ED) patients with recent onset (less than one month) of exertional dyspnea? Dr....
Article
Anticoagulation for AFib Increases Bleeding Risk and Death in Patients Over 65 with Cognitive Impairment
December 1, 2023
Clinical question: In older patients with atrial fibrillation (AFib), does frailty or cognitive function affect the risk of anticoagulation use? Dr. Enix Background: In older patients with...
Article
Administering Glucocorticoids Lowers Risk of Death in ICU Patients with Severe CAP
December 1, 2023
Clinical question: Does early administration of glucocorticoids to intensive care unit (ICU) patients with severe community-acquired pneumonia (CAP) reduce mortality? Ms. Harakal Background:...
Article
Gaps Remain in Hospital Discharge Education
December 1, 2023
Clinical question: What are medicine floor patients told about their hospital discharge instructions and by whom? Dr. Mutter Background studies: Prior studies have demonstrated suboptimal...
Article
Systemic Corticosteroids for Patients with Severe CAP
December 1, 2023
Clinical question: Among patients hospitalized with community-acquired pneumonia (CAP), does the addition of corticosteroids reduce mortality? Dr. Salline Background: Corticosteroids are used...