Article
Semaglutide reduces major adverse cardiovascular events by 20% in patients with cardiovascular disease
June 3, 2024
Clinical question: Does semaglutide reduce cardiovascular events in non-diabetics with cardiovascular disease? Background: While glucagon-like peptide-1 (GLP-1) agonists reduce cardiovascular events...
Article
Comparing in-hospital adverse events in elderly postoperative delirium patients: haloperidol versus atypical antipsychotics
June 3, 2024
Clinical question: Are in-hospital adverse events worse in post-operative delirium patients treated with haloperidol compared to atypical antipsychotics? Background: Post-operative delirium is...
Article
Hydrocortisone reduces mortality in severe CAP
June 3, 2024
Clinical question: Does early hydrocortisone therapy reduce mortality among patients with severe community-acquired pneumonia (CAP) requiring admission to an intensive care unit (ICU) or intermediate...
Article
Apixaban Reduces Risk of Stroke or Systemic Embolism in Subclinical AF
May 1, 2024
Dr. Watson Clinical question: Does oral anti-coagulation reduce stroke or systemic embolism risk in subclinical atrial fibrillation (AF)? Background: Studies have shown an increased risk of...
Article
High Frequency of AF Recurrence in Hospitalized Patients with New-onset AF
May 1, 2024
Dr. Watson Clinical question: What is the frequency of atrial fibrillation (AF) recurrence in patients with new-onset AF, detected while hospitalized for a noncardiac medical illness or surgery,...
Article
SGLT-2 inhibitors May Decrease Recurrent Gout Flares in Patients with Type 2 diabetes
May 1, 2024
Dr. Bernal Clinical question: Do SGLT-2 inhibitors decrease gout flares in patients with type 2 diabetes and a known history of gout? Background: Sodium–glucose cotransporter-2 inhibitors...
Article
Semaglutide in Patients with HFpEF and Obesity
May 1, 2024
Dr. Cepeda Mora Clinical question: Is semaglutide an effective heart failure treatment in patients with heart failure with preserved ejection fraction (HFpEF) and obesity? Background: HFpEF is...
Article
Frailty Assessment and Perioperative Adverse Cardiovascular Events After Noncardiac Surgery
May 1, 2024
Dr. Chandler Clinical question: Can a frailty assessment tool be used to identify patients at higher risk for major adverse cardiac events (MACE) prior to noncardiac surgery? Background: Studies...
Article
Black Patients More Likely to Experience Security Emergency Responses
May 1, 2024
Colby Feeney, MD, FHM Clinical question: Do race and ethnicity predict the use of security emergency responses (SER) in a non-psychiatric inpatient setting? Background: Studies have demonstrated...
Article
Piperacillin-tazobactam Doesn’t Increase Risk of AKI Compared to Cefepime
May 1, 2024
Dr. Rhodes Clinical question: Do piperacillin-tazobactam and cefepime have similar risks of acute kidney injury (AKI)? Background: Observational studies have shown an association between...