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An Official Publication of
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In the Literature

  • Article

    Periprocedural Management of Patients with AF Receiving a DOAC Undergoing a Digestive Endoscopy

    March 1, 2024

    Clinical question: How long should patients with atrial fibrillation (AF) on a direct oral anticoagulant (DOAC) hold anticoagulation when undergoing endoscopy? Background: Given limited direct...

  • Article

    DOACs Versus LMWH and Recurrent VTE in Patients with Cancer

    March 1, 2024

    Clinical question: Are direct oral anticoagulants (DOACs) acceptable compared to low-molecular-weight heparin (LMWH) for preventing venous thromboembolism (VTE) with a safe bleeding risk in cancer...

  • Article

    Opioids Confer Risk without Improved Pain Control

    March 1, 2024

    Clinical question: How effective and safe are opioids for the treatment of acute, non-specific low back and neck pain? Background: Despite the lack of evidence of the effectiveness of opioids for...

  • Article

    Reducing Use of NPO After Midnight for Inpatient Diagnostic and Therapeutic Procedures

    March 1, 2024

    Clinical question: Can an interprofessional quality improvement team reduce the use of nil per os (NPO) after midnight orders prior to inpatient diagnostic and therapeutic procedures requiring...

  • Article

    Aspirin Thromboprophylaxis is Non-inferior to LMWH for Prevention of Death and Pulmonary Embolism after Orthopedic Trauma

    March 1, 2024

    Clinical question: Is aspirin as effective as low-molecular-weight heparin (LMWH) for thromboprophylaxis in patients with orthopedic trauma? Background: Studies have outlined the benefits of...

  • Article

    Adult Hospitalizations from Immigration-detention Facilities

    February 1, 2024

    Dr. Woodruff Clinical question: What are the causes of hospitalizations from immigration-detention facilities and what is their relative morbidity? Background: Over the last three decades, an...

  • Article

    Virtual Care Team Increases the Number of Patients with CHF on GDMT During Hospitalization

    February 1, 2024

    Dr. Pahwa Clinical question: Can a virtual care team increase the number of patients with chronic heart failure (CHF) on goal-directed therapy during hospitalization? Background: Maximizing...

  • Article

    Fewer COPD Exacerbations and Pneumonia Hospitalizations with LABA-LAMA Inhalers Compared to ICS-LABA in COPD

    February 1, 2024

    Dr. Coursen Clinical question: Is a long-acting beta agonist and long-acting muscarinic antagonist (LABA-LAMA) inhaler combination better than an inhaled corticosteroid and long-acting beta...

  • Article

    No Clear Benefit to the Use of Haloperidol for ICU Delirium

    February 1, 2024

    Dr. Leventhal Clinical question: Does the use of haloperidol versus placebo for delirium in ICU patients improve mortality and increase the chance of hospital discharge at 90 days? Background:...

  • Article

    Transcatheter Repair of Secondary Mitral Regurgitation Improves Outcomes

    February 1, 2024

    Dr. Asmar Clinical question: Does transcatheter mitral valve repair of secondary mitral regurgitation improve hospitalization rates and mortality in patients with refractory symptoms despite...

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