Article
Carvedilol Versus Propranolol for the Prevention of Decompensation and Mortality in Patients with Compensated and Decompensated Cirrhosis
July 31, 2025
Clinical question: Is carvedilol more effective than the classical non-selective beta-blockers (cNSBBs) propranolol or nadolol in preventing first decompensation and in reducing mortality in patients...
Article
Time to Rethink SBP. Do the Harms Outweigh the Benefits?
July 31, 2025
Clinical question: In the context of increasing antibiotic resistance and changing microbiology of Spontaneous Bacterial Peritonitis (SBP), does secondary SBP prophylaxis reduce the recurrence of SBP...
Article
Ammonia Levels Do Not Reflect Severity of Hepatic Encephalopathy in Hospitalized Patients with Cirrhosis
April 1, 2025
Clinical question: Do serum ammonia levels correlate with the severity of overt hepatic encephalopathy (OHE) in hospitalized patients with cirrhosis? Background: Guidelines recommend diagnosing OHE...
Article
Higher Rates of Major Hemorrhage with Rivaroxaban and Warfarin
December 2, 2024
Clinical question: How effective and safe are apixaban versus rivaroxaban versus warfarin in patients with cirrhosis and nonvalvular atrial fibrillation (AF)? Background: Apixaban, rivaroxaban, and...
Article
Interpretation of Serum Ammonia Level
December 2, 2024
A 77-year-old woman with a history of hepatitis C cirrhosis presents to the emergency department with 24 hours of progressive confusion and disorientation. The physical exam is notable for...
Article
P2Y12 Inhibitor Monotherapy After 1-3 Months of DAPT Reduces Major Bleeding Risk Without Increasing Ischemic Risk After Complex PCI
October 2, 2023
Clinical question: Does P2Y12 inhibitor monotherapy after one to three months of dual antiplatelet therapy (DAPT) improve clinical decrease in major bleeding risk without increasing ischemic risk in...
Article
The 2022 AAP Newborn Jaundice Guideline: Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation
July 5, 2023
Dr. Holmes presented the 2022 American Academy of Pediatrics Clinical Practice Guideline for Management of Hyperbilirubinemia in the Newborn Infant 35 or More Weeks of Gestation. A large, diverse...
Article
Inpatient Management of Decompensated Cirrhosis
July 5, 2023
In this clinical-pearl-packed session, Dr. Suchita Shah Sata from Duke University Hospital in Durham, N.C., recaps the breadth of knowledge needed by hospitalists to manage this complex patient...
Article
Updates on Gastroenterology and Hepatology
July 5, 2023
Dr. Sears’s fun, fast-paced speaking style peppered with her wellness moments (and El Arroyo quotes) always make for an excellent learning experience. Her quick recap on acute pancreatitis...
Article
Duration of Abstinence from Alcohol Prior to Liver Transplantation Does Not Lead to Increased Survival in Patients with Alcohol-related Liver Disease
March 1, 2023
Clinical question: How does the duration of abstinence from alcohol affect patient survival, allograft survival, and relapse-free survival in patients undergoing liver transplantation? Background:...