Caprini score is not a good predictor of PE in patients with DVT
October 25, 2017
Commonly used model failed to predict pulmonary embolism in patients with DVT.
September 26, 2017
Clinical question: Is hospital acquired anemia associated with increased postdischarge adverse outcomes?
Idarucizumab reversed dabigatran completely and rapidly in study
July 11, 2017
One drug reversed the anticoagulant effect of another completely and rapidly.
Application of the MASCC and CISNE risk-stratification scores to identify low-risk febrile neutropenic patients in the emergency department
June 12, 2017
Does the Multinational Association for Supportive Care in Cancer (MASCC) or Clinical Index of Stable Febrile Neutropenia (CISNE) risk-stratification score better predict patient outcomes in patients presenting to emergency departments with febrile neutropenia?
Low-dose aspirin bests dual-antiplatelet therapy in TAVR
June 8, 2017
PARIS – ARTE trial is hailed as practice changing.
Consider switch to clopidogrel for DAPT early post ACS
May 20, 2017
PARIS – TOPIC trial provides new evidence-based DAPT strategy.
What are indications, complications of acute blood transfusions in sickle cell anemia? Key Points Additional Reading
March 17, 2017
Transfusion has many serious and life-threatening potential adverse effects; conduct thorough risk-benefit analysis for each individual sickle cell patient. Whenever possible, intensive phenotypically matched and leukoreduced RBCs should be used.
Taking the hammer to sickle pain crises
February 1, 2017
Clinical question: Are any novel medicines designed to interrupt the pathophysiology of vaso-occlusion available to reduce the frequency and severity of pain crises in sickle cell anemia?
Blood thinning with bioprosthetic valves
January 10, 2017
Blood thinning with bioprosthetic valvesClinical question: Does anticoagulation prevent thromboembolic events in patients undergoing bioprosthetic valve implantation?Background: The main advantage of bioprosthetic valves, compared with mechanical valves, is the avoidance of long-term anticoagula...
Increased death rate with platelets for aspirin/clopidogrel GI bleed
November 28, 2016
Patients with normal platelet counts who have a GI bleed while on antiplatelets were almost six times more likely to die in the hospital if they had a platelet transfusion, in a retrospective cohort study from the Yale University.