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Hematology (blood)

  • Article

    Gram-Negative Bacteremia: Early Transition from IV to PO Antibiotic Therapy

    March 4, 2025

    Clinical question: What is the safety and efficacy of switching from IV to oral antibiotic therapy after three to five days in patients with gram-negative bacteremia? Background: Bacteremia is...

  • Article

    Slower Correction of Sodium in Severe Hyponatremia is Associated with Increased Mortality and Length of Stay

    March 4, 2025

    Clinical question: Is the sodium correction rate in severe hyponatremia associated with mortality and length of stay? Background: Hyponatremia is commonly encountered in the hospital, with high...

  • Article

    Interpretation of Serum Ammonia Level

    December 2, 2024

    A 77-year-old woman with a history of hepatitis C cirrhosis presents to the emergency department with 24 hours of progressive confusion and disorientation. The physical exam is notable for...

  • Article

    When Should I Transfuse My Adult Hospitalized Patient Who Has Anemia?

    December 2, 2024

    Update to the 2017 article When should I transfuse a patient who has anemia?  Case An 82-year-old woman with chronic lymphocytic leukemia complicated by anemia of chronic disease (baseline...

  • Article

    Challenging Anticoagulation Scenarios: How to Have Smooth Sailing through Choppy Waters

    July 1, 2024

    Keeping abreast of updates in anticoagulation guidelines is important for physicians to provide optimal patient care. Multiple changes to recommendations for anticoagulation have been made in the...

  • Article

    Solving Major Problems: Major Bleeding and Major Surgery for Patients on Anticoagulants

    July 1, 2024

    This interactive session posed real-life scenarios for hospitalists who frequently deal with difficult anticoagulation questions and grounded it all with the evidence. The first case discussed was...

  • Article

    Is 7 Really the Magic Number for RBC Transfusion?

    May 1, 2024

      Over the past decade, there has been widespread adoption of restrictive red blood cell (RBC) transfusion guidelines.1,2 As a result, RBC transfusions have significantly decreased per...

  • Article

    Can Pentoxifylline Improve Healing of Lower Extremity Ulcers?

    May 1, 2024

    Case The patient, Mr. D, has been experiencing swelling in his legs for several years, and seven months prior, he noticed that his skin had started to develop ulcers. He has class 3 obesity, type 2...

  • Article

    Use of Amiodarone with Apixaban or Rivaroxaban Increases Risk for Bleeding-related Hospitalizations

    March 1, 2024

    Clinical question: Does the use of amiodarone in patients with atrial fibrillation increase the risk for bleeding-related hospitalizations when used with apixaban or rivaroxaban? Background:...

  • Article

    ODS in Hospitalized Patients with Hyponatremia

    September 1, 2023

    Dr. Mohoney Clinical question: Of the patients who are admitted with hyponatremia, how many develop osmotic demyelination syndrome (ODS)? Background: ODS is a rare but serious complication...

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