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An Official Publication of
  • Clinical
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Pharmacology

  • Article

    Oral Tebipenem Pivoxil Hydrobromide is Noninferior to IV Ertapenem in Complicated UTI

    April 3, 2023

    Dr. Modha Clinical question: Is oral carbapenem tebipenem effective in treating complicated urinary tract infections (UTIs)? Background: Antimicrobial resistance among pathogens, especially...

  • Article

    Association of Chronic Medication Adherence with ED Visits and Hospitalizations

    April 3, 2023

    Dr. Gibson Clinical question: Is there an association between chronic medication adherence and emergency department (ED) visits and hospitalizations? Background: Medication adherence for...

  • Article

    Antibiotic Overuse After Discharge: A Multi-hospital Cohort Study

    March 1, 2023

    Clinical question: Do patients need continued antibiotics after leaving the hospital? Background: Despite inpatient antimicrobial stewardship programs, studies suggest that up to half of antibiotics...

  • Article

    Acetaminophen Rises Systolic Blood Pressure in Those with Hypertension

    March 1, 2023

    Clinical question: Does regular intake of acetaminophen cause an increase in blood pressure? Background: Acetaminophen is one of the most commonly used analgesics in the world. Because of its...

  • Article

    Effectiveness of Oxycodone Hydrochloride vs. Combination Acetaminophen and Codeine for Subacute Pain After Fractures Managed Surgically: A Randomized Controlled Trial

    March 1, 2023

    Clinical question: Do less potent opioids suffice for adequate pain control for patients with surgically managed fractures? Background: For post-surgical pain management at time of discharge,...

  • Article

    Breaking News: X-waiver Eliminated

    January 25, 2023

    On January 12, 2023, the U.S. Drug Enforcement Administration (DEA) and the Substance Abuse and Mental Health Services Administration (SAMHSA) announced the immediate elimination of the X-waiver for...

  • Article

    Update: Caring for COVID-19 Patients in the Hospital

    January 3, 2023

    Severe cases of COVID-19 infections continue to necessitate hospitalization more than two and a half years after the pandemic first hit. A total of 26,996 patients were hospitalized with COVID-19 in...

  • Article

    Cephalosporins: How Vital Are They in a Hospitalist’s Toolkit?

    December 1, 2022

    Case A 57-year-old female with a history of hypertension and diabetes mellitus presented to the emergency department with complaints of chills, fever, and productive cough progressively worsening...

  • Article

    Oral Antibiotics and a Combination Regimen of IV and Oral Antibiotics for Treatment of Acute Uncomplicated Appendicitis Yielded Similar Success Rates

    September 1, 2022

    Dr. Andleeb Clinical question: Are oral antibiotics effective and non-inferior to a combination of intravenous and oral antibiotics?  Background: Evidence over the past 10 years suggests that...

  • Article

    Low-dose Rivaroxaban at Discharge Prevented Some VTE Events at One Month for High-risk Patients Recovering from COVID-19

    September 1, 2022

    Dr. Thazhatuveetil-Kunhahamed Clinical Question: Is extended rivaroxaban prophylaxis (10 mg daily for 35 days) protective against arterial and venous thromboembolism (VTE) events in COVID-19...

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