No difference between balanced multi-electrolyte solution versus saline in critically ill adults
April 1, 2022
Dr. Knoeckle Clinical question: Does the use of a balanced multi-electrolyte solution (BMES) for fluid resuscitation in adults admitted to an intensive-care unit (ICU) impact 90-day...
D-dimer thresholds rule out PE in meta-analysis
December 14, 2021
Data from a large review support use of D-dimer levels to diagnose PE without imaging.
Timing of initiation of renal-replacement therapy in acute kidney injury
December 8, 2021
In critically ill patients, does early renal-replacement therapy (RRT), compared with standard therapy, improve death from any cause at 90 days?
Predicting cardiac shock mortality in the ICU
November 23, 2021
Including biventricular dysfunction as assessed using transthoracic echocardiography improves clinical risk stratification.
Timing of renal-replacement therapy for AKI in the ICU
November 19, 2021
Does earlier initiation of renal-replacement therapy (RRT) improve mortality in the ICU?
Faster testing possible for secondary ICU infections
November 18, 2021
Researchers have shown the potential for clinical metagenomics to become a same-day test for identifying secondary infection in ventilated ICU patients.
Hospitalists helped plan COVID-19 field hospitals
November 18, 2021
Better to plan for too much than not plan for enough, say hospitalists who helped build COVID-19 field hospitals.
Droperidol/midazolam combo curbs agitation in ED patients
November 2, 2021
A combination of haloperidol and lorazepam has been widely used to curb agitation in these patients, but droperidol and midazolam could be more effective, owing to faster onset of action.
Benefit of combined ascorbic acid, corticosteroids, and thiamine in septic shock remains unproven
October 25, 2021
Does the combination of ascorbic acid, corticosteroids, and thiamine attenuate organ injury in septic shock?
Sepsis multiplies in-hospital mortality risk in COPD
October 21, 2021
Among nearly 7 million hospitalizations in which the primary diagnosis was COPD, nearly 65,000 (0.93%) patients experienced sepsis as a complication.