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Circulatory

  • News

    AstraZeneca COVID vaccine: Clotting disorder mechanism revealed?

    April 2, 2021

    The vaccine may be linked to a condition that clinically resembles heparin-induced thrombocytopenia and seems to occur mainly in younger women.

  • News

    ‘Major update’ of BP guidance for kidney disease; treat to 120 mm Hg

    March 16, 2021

    “[Chapter one] of the guidelines is devoted to blood pressure measurement ... if [targeting] 120 [mm Hg systolic], the emphasis is on 120 measured properly.”

  • 1
    News

    DOACs offered after heart valve surgery despite absence of data

    March 9, 2021

    Use of direct oral anticoagulants following heart valve surgery is occurring despite relative contraindications, but expert doubts its clinical significance.

  • News

    Late-window stroke thrombolysis not linked to clot migration

    March 3, 2021

    This is the first randomized controlled study to assess the effect of thrombolysis on clot migration and accessibility in an extended time window.

  • News

    Microthrombi, necrosis seen in COVID-19 hearts on autopsy

    February 3, 2021

    A new autopsy series shows microthrombi and focal necrosis in hearts of patients who died of COVID-19. The findings support use of anticoagulation, but best dosing remains unclear, researchers say.

  • 1
    News

    DAPT increases bleeding without decreasing mortality in patients with coronary disease and diabetes

    February 2, 2021

    In patients who have diabetes with known coronary disease but without prior MI or stroke, what is the effect of dual-antiplatelet therapy (DAPT) with aspirin and ticagrelor on cardiovascular outcomes and bleeding events?

  • 1
    News

    Anticoagulation and antiplatelet therapy after GI bleed cut mortality, ischemic events

    January 28, 2021

    In patients who present with a gastrointestinal bleed (GIB) while on an anticoagulants (AC) or antiplatelets (AP), what are the risks and benefits to resuming these medications?

  • News

    Full-dose anticoagulation reduces need for life support in COVID-19

    January 25, 2021

    “We have treatments that are improving outcomes but not as many that reduce mortality, so we’re hopeful when the full dataset comes in that will be confirmed.”

  • 1
    News

    DOACs show safety benefit in early stages of CKD

    January 15, 2021

    In terms of efficacy and bleeding risk, what is known about anticoagulation in patients with chronically impaired renal function?

  • 1
    News

    A standardized approach to postop management of DOACs in AFib

    January 13, 2021

    Is it safe to adopt a standardized approach to direct oral anticoagulant (DOAC) interruption for patients with atrial fibrillation (AFib) who are undergoing elective surgeries/procedures?

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