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An Official Publication of
  • Clinical
    • In the Literature
    • Key Clinical Questions
    • Interpreting Diagnostic Tests
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Circulatory

  • Article

    Higher-than-expected recurrent VTE found in patients with isolated SSPE

    April 1, 2022

    Dr. Munoa Clinical question: What is the recurrence rate of venous thromboembolism (VTE) in patients with isolated subsegmental pulmonary embolisms (SSPE) managed without...

  • Article

    Direct oral anticoagulants may be safe in cancer-related venous thromboembolisms, but use caution with gastrointestinal malignancies

    February 3, 2022

    Clinical question: Are direct oral anticoagulants (DOACs) a suitable alternative to low molecular weight heparin (LMWH) for treatment of venous thromboembolism (VTE) in patients with underlying...

  • News

    D-dimer thresholds rule out PE in meta-analysis

    December 14, 2021

    Data from a large review support use of D-dimer levels to diagnose PE without imaging.

  • 1
    News

    Anticoagulant choice in antiphospholipid syndrome–associated thrombosis

    December 10, 2021

    Are direct oral anticoagulants (DOACs) as efficacious and safe as vitamin K antagonists (VKAs) in treating thrombosis secondary to antiphospholipid syndrome (APS)?

  • 1
    News

    Apixaban a reasonable alternative to warfarin in patients with severe renal impairment

    December 9, 2021

    Is apixaban a safe alternative to warfarin in patients with severe renal impairment?

  • 1
    News

    Apixaban outmatches rivaroxaban for VTE in study

    December 6, 2021

    These real-world findings may guide selection of initial anticoagulant therapy, according to authors of the paper.

  • 1
    News

    Apixaban noninferior to low-molecular-weight heparin in cancer-associated VTE

    December 6, 2021

    Is oral apixaban as safe and effective as subcutaneous dalteparin in treating venous thromboembolism (VTE) in patients with underlying cancer?

  • 1
    News

    Ticagrelor reversal agent achieves quick hemostasis: REVERSE-IT

    November 17, 2021

    The monoclonal antibody bentracimab, which can rapidly reverse ticagrelor, was found effective and safe in an FDA-requested interim analysis of a phase 3 trial.

  • News

    D-dimer unreliable for ruling out pulmonary embolism in COVID-19

    October 14, 2021

    “These results suggest that use of D-dimer levels to exclude PE among patients hospitalized with COVID-19 may be inappropriate and have limited clinical utility.”

  • 1
    News

    Autopsy findings reveal venous thromboembolism in patients with COVID-19

    October 12, 2021

    What pathologic features contribute to the cause of death in COVID-19?

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