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ColCORONA: More questions than answers for colchicine in COVID-19
February 11, 2021
Millions of dollars and thousands of patients later, the phase 3 study highlights the challenges of COVID-19–related preprint studies without peer review.
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Cardiac activity not uncommon after lifesaving measures stop
February 5, 2021
ECG and blood pressure monitoring identified resumption of cardiac activity in 14% of patients, all occurring in the 5 minutes after pulselessness.
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Complete PCI beats culprit-lesion-only PCI in STEMI patients with multivessel CAD
February 3, 2021
In patients who have a STEMI (ST elevation myocardial infarction) and are found to have multivessel coronary artery disease, does staged percutaneous coronary intervention (PCI) of nonculprit lesions improve cardiovascular death or MI?
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Microthrombi, necrosis seen in COVID-19 hearts on autopsy
February 3, 2021
A new autopsy series shows microthrombi and focal necrosis in hearts of patients who died of COVID-19. The findings support use of anticoagulation, but best dosing remains unclear, researchers say.
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DAPT increases bleeding without decreasing mortality in patients with coronary disease and diabetes
February 2, 2021
In patients who have diabetes with known coronary disease but without prior MI or stroke, what is the effect of dual-antiplatelet therapy (DAPT) with aspirin and ticagrelor on cardiovascular outcomes and bleeding events?
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Newer iPhones disable implanted defibrillators
February 1, 2021
Some newer smartphones are equipped with magnets sufficiently powerful to disable an implanted cardiac defibrillator.
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Neprilysin, corin singled out for potential to guide heart failure therapy
January 28, 2021
Circulating neprilysin and corin concentrations, which correlate with outcomes, could possibly be assessed to guide heart failure therapy.
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Myocarditis by CMR may be rare after COVID-19 in elite athletes
January 27, 2021
Some supposed ‘myocarditis’ detected by MRI after COVID-19 in university varsity competitors might be normal heart muscle – normal for athletes, that is, propose researchers.
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Full-dose anticoagulation reduces need for life support in COVID-19
January 25, 2021
“We have treatments that are improving outcomes but not as many that reduce mortality, so we’re hopeful when the full dataset comes in that will be confirmed.”
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Think twice before intensifying BP regimen in older hospitalized patients
January 20, 2021
Does intensifying antihypertensive regimens in older patients hospitalized for noncardiac conditions lead to better long-term blood pressure control or does this practice potentially cause harm?
