Article
Benefits of Triple Inhaler Therapy for Patients with Moderate to Severe Asthma
December 1, 2022
Dr. Magee Clinical Question: Does triple inhaler therapy improve outcomes over dual inhaler therapy in patients with moderate to severe asthma? Background: For patients with moderate and severe...
Article
Prediction of End-stage Kidney Disease Using Estimated Glomerular Filtration Rate With and Without Race
October 3, 2022
Dr. Choksi Clinical question: Does using old and new chronic kidney disease epidemiology collaboration (CKD-EPI) equations alone have a better predictive value for two-year incidence of end-stage...
Article
Antiplatelet Therapy Does Not Improve Outcomes in Critically Ill Patients With COVID-19 and May Increase the Risk of Bleeding
October 3, 2022
Clinical question: Do antiplatelet agents improve organ support-free days among critically ill adults with COVID-19? Background: COVID-19 is known to increase the risk for thrombotic events, and...
Article
International Validation of Syncope Risk Assessment Score
October 3, 2022
Dr. Fritz Clinical question: Does the Canadian Syncope Risk Score (CSRS) compare favorably to another scoring system, Osservatorio Epidemiologico della Sincope nel Lazio (OESIL) in predicting...
Article
Sodium-containing Acetaminophen Intake Increases the Risk of CVD and All-cause Mortality
October 3, 2022
Dr. Hoque Clinical question: Does the use of sodium-containing acetaminophen increase the risk of cardiovascular disease (CVD) and all-cause mortality in patients with and without a history of...
Article
CT Coronary Angiography in Stable Intermediate-risk Chest Pain
October 3, 2022
Dr. Mayer Clinical question: Is it safe to perform computed tomography (CT) coronary angiography to rule out obstructive coronary artery disease (CAD) in patients with stable intermediate-risk...
Article
Antiplatelet Medications and the Risk of ICH in Patients with Metastatic Brain Tumors
October 3, 2022
Dr. Vaidyan Clinical question: Do antiplatelet medications increase the risk of intracranial hemorrhage (ICH) in patients with metastatic brain tumors? Background: Brain metastases increase...
Article
There is a Decreased Risk of Hospitalization from Heart Failure in Type II Diabetics Initiated on a SGLT2 Inhibitor When Compared to a GLP-1 Receptor Agonist
September 1, 2022
Dr. Huang Clinical question: Determine the cardiovascular risk outcome in type II diabetic patients initiated on an sodium-glucose cotransporter-2 (SGLT2) inhibitor versus a glucagon-like...
Article
Transthoracic Echocardiography is Superior in Detecting Valvular Heart Disease
September 1, 2022
Ms. Nowak Clinical question: To quantify the extent to which undetectable heart sounds occur in hospitalized patients who are undergoing transthoracic echocardiography and evaluate the...
Article
Acute Care for the Elderly in the Home Environment Increased Physical Activity Levels While Lowering Costs, Health Care Use, and Readmissions
September 1, 2022
Dr. Nagaraj Clinical question: Can hospital-level care be provided in the home environment to reduce costs without compromising the quality of care in the U.S.? Background: Inpatient care is...