Article
ODS in Hospitalized Patients with Hyponatremia
September 1, 2023
Dr. Mohoney Clinical question: Of the patients who are admitted with hyponatremia, how many develop osmotic demyelination syndrome (ODS)? Background: ODS is a rare but serious complication...
Article
Acetazolamide in Acute Decompensated Heart Failure With Volume Overload
September 1, 2023
Dr. Chadwick Clinical question: Does the addition of acetazolamide to standardized loop diuretic therapy achieve more effective decongestion compared to loop diuretics alone in acute...
Article
Postsurgical Delirium Predicts Long-term Cognitive Decline
September 1, 2023
Dr. Gordon Clinical question: How does postsurgical delirium impact cognitive performance over a six-year follow-up period? Background: Delirium is a challenging syndrome that is frequently...
Article
Consider Platelet Transfusion Prior to CVC Placement for Patients with High-risk Thrombocytopenia
September 1, 2023
Dr. Meyer Clinical question: Can central venous catheters (CVC) be safely placed in patients with platelet counts less than 50,000 without administration of platelets prior to the...
Article
Summary of the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2023 Report
September 1, 2023
Dr. Long Clinical question: How did GOLD revise its prior recommendations for the diagnosis and management of chronic obstructive pulmonary disease (COPD)? Background: The World Health...
Article
Diagnostic Yield of Head CT in Delirium and Altered Mental Status
September 1, 2023
Dr. Long Clinical question: What is the diagnostic utility of a head CT in hospitalized patients with delirium or altered mental status (AMS) across a variety of clinical settings and what...
Article
Surgery May Be Better Than Endovascular Intervention for Some CLTI Patients
June 1, 2023
Dr. Fadden Clinical question: Which is a better approach for patients with chronic limb-threatening ischemia (CLTI): surgery or endovascular therapy? Background: CLTI is a complication of...
Article
Recurrence of VTE Associated with COVID-19 is Unlikely After Stopping Anticoagulation
June 1, 2023
Dr. Sullivan Clinical question: How long should anticoagulation be continued after COVID-19-associated venous thromboembolism (VTE)? Background: COVID-19 infection is associated with an...
Article
Using Naltrexone for AUD is Safe in Patients With and Without Liver Disease
June 1, 2023
Dr. Hoang Clinical question: Is naltrexone hepatically safe for the treatment of alcohol use disorder (AUD) in patients with and without liver disease? Background: Treatment of underlying AUD...
Article
Moderate Fluid Resuscitation Preferred Over Aggressive Resuscitation in Acute Pancreatitis
June 1, 2023
Dr. Houston Clinical question: Does early, aggressive, fluid resuscitation improve clinical outcomes in acute pancreatitis when compared to moderate fluid resuscitation? Background: Studies...