Article
Aspirin Thromboprophylaxis is Non-inferior to LMWH for Prevention of Death and Pulmonary Embolism after Orthopedic Trauma
March 1, 2024
Clinical question: Is aspirin as effective as low-molecular-weight heparin (LMWH) for thromboprophylaxis in patients with orthopedic trauma? Background: Studies have outlined the benefits of...
Article
Adult Hospitalizations from Immigration-detention Facilities
February 1, 2024
Dr. Woodruff Clinical question: What are the causes of hospitalizations from immigration-detention facilities and what is their relative morbidity? Background: Over the last three decades, an...
Article
Virtual Care Team Increases the Number of Patients with CHF on GDMT During Hospitalization
February 1, 2024
Dr. Pahwa Clinical question: Can a virtual care team increase the number of patients with chronic heart failure (CHF) on goal-directed therapy during hospitalization? Background: Maximizing...
Article
Fewer COPD Exacerbations and Pneumonia Hospitalizations with LABA-LAMA Inhalers Compared to ICS-LABA in COPD
February 1, 2024
Dr. Coursen Clinical question: Is a long-acting beta agonist and long-acting muscarinic antagonist (LABA-LAMA) inhaler combination better than an inhaled corticosteroid and long-acting beta...
Article
No Clear Benefit to the Use of Haloperidol for ICU Delirium
February 1, 2024
Dr. Leventhal Clinical question: Does the use of haloperidol versus placebo for delirium in ICU patients improve mortality and increase the chance of hospital discharge at 90 days? Background:...
Article
Transcatheter Repair of Secondary Mitral Regurgitation Improves Outcomes
February 1, 2024
Dr. Asmar Clinical question: Does transcatheter mitral valve repair of secondary mitral regurgitation improve hospitalization rates and mortality in patients with refractory symptoms despite...
Article
Abatacept and Infliximab May Improve Mortality in Patients Hospitalized with COVID-19 Pneumonia
February 1, 2024
Dr. Rose Clinical question: What immunomodulatory drugs should we use in hospitalized patients with COVID-19 in addition to corticosteroids? Background: Inflammation is a key driver of morbidity...
Article
Risk Stratification of Patients with HF in the ED Coupled with Close Outpatient Follow-up Reduces Mortality and CV Rehospitalization
February 1, 2024
Dr. Latifi Clinical question: In patients presenting to the emergency department (ED) with heart failure (HF) symptoms, are patient outcomes affected by the use of a risk stratification tool to...
Article
Risk for CKD Progression After AKI
February 1, 2024
Dr. Dalal Clinical question: Is acute kidney injury (AKI) associated with subsequent worsening of renal function trajectory in patients with chronic kidney disease (CKD)? Background: Prior...
Article
Partial Oral Antibiotic Therapy May be Effective in Treating Complicated MRSA Among People with IDU
December 1, 2023
Clinical question: Are oral antibiotics effective in completing treatment for complicated methicillin-resistant Staphylococcus aureus (MRSA) among patients with injection drug use (IDU)? Dr....