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Clinical

  • News

    Interdisciplinary Intervention Improves Medication Compliance, Not Blood Pressure or LDL-C Levels

    October 27, 2014

    Clinical question: Can intervention by pharmacists and physicians improve compliance to cardio-protective medications? Background: Adherence to cardio-protective medications in the year after hospitalization for acute coronary syndrome is poor. Study design: RCT. Setting: Four Department of

  • News

    Colloids vs. Crystalloids for Critically Ill Patients Presenting with Hypovolemic Shock

    October 27, 2014

    Clinical question: In critically ill patients admitted to the ICU with hypovolemic shock, does the use of colloid for fluid resuscitation, compared with crystalloid, improve mortality? Background: The current Surviving Sepsis Campaign guidelines recommend crystalloids as the preferred fluid for r

  • News

    “Triple Rule Outs” for Chest Pain: A Tool to Evaluate the Coronaries but Not Pulmonary Embolism or Aortic Dissection

    October 27, 2014

    Clinical question: How does “triple rule out” (TRO) computed tomographic (CT) angiography compare to other imaging modalities in evaluating coronary and other life-threatening etiologies of chest pain, such as pulmonary embolism (PE) and aortic dissection? Background: TRO CT angiography is a noni

  • News

    Patients Prefer Inpatient Boarding to Emergency Department Boarding

    October 27, 2014

    Clinical question: Do patients who experience overcrowding and long waits in the emergency department (ED) prefer boarding within ED hallways or within inpatient medical unit hallways? Background: Boarding of admitted patients in EDs can be problematic, especially with regard to patient safety an

  • News

    Benefit of Therapeutic Hypothermia after Cardiac Arrest Unclear

    October 27, 2014

    Clinical question: Does targeted hypothermia (33°C) after cardiac arrest confer benefits compared with targeted temperature management at 36°C? Background: Therapeutic hypothermia is a current recommendation in resuscitation guidelines after cardiac arrest.

  • News

    Pre-Operative Beta Blockers May Benefit Some Cardiac Patients

    October 27, 2014

    Clinical question: In patients with ischemic heart disease (IHD) undergoing non-cardiac surgery, do pre-operative beta blockers reduce post-operative major cardiovascular events (MACE) or mortality at 30 days? Background: Peri-operative beta blocker use has become more restricted, as evidence abo

  • News

    Facecards Improve Familiarity with Physician Names but Not Satisfaction

    October 27, 2014

    Clinical question: Do facecards improve patients’ familiarity with physicians and increase satisfaction, trust, and agreement with physicians? Background: Facecards can improve patients’ knowledge of names and roles of physicians, but their impact on other outcomes is unclear.

  • News

    New Oral Anticoagulants Safe and Effective for Atrial Fibrillation Treatment

    October 27, 2014

    Clinical question: Is there a difference in efficacy and safety among new oral anticoagulants compared to warfarin in subgroups of patients with atrial fibrillation (Afib)? Background: Studies of new oral anticoagulants have demonstrated that these agents are at least as safe and effective as war

  • News

    Sepsis Diagnoses Are Common in ED, but Many Septic Patients in the ED Do Not Receive Antibiotics

    October 27, 2014

    Clinical question: Has the frequency of sepsis rates, along with administration of antibiotics in U.S.

  • News

    Multifaceted Discharge Interventions Reduce Rates of Pediatric Readmission and Post-Hospital ED Utilization

    October 27, 2014

    Clinical question: Do interventions at discharge reduce the rate of readmissions and post-hospitalization ED visits among pediatric patients? Background: Readmissions are a high-priority quality measure in both the adult and pediatric settings.

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