Article
When Less is More: How to Provide Less Anticoagulant and Antiplatelet Treatment to Improve Outcomes
July 1, 2026
As hospitalists, we are often trained to err on the side of doing more, especially in the ways we have historically approached anticoagulation and antiplatelet therapies. Faced with the competing...
Article
When Less Is More: Aspirin in Patients with Chronic Coronary Syndrome Receiving Oral Anticoagulation
June 18, 2026
Mount Sinai Med-Lit Review Clinical Question: In patients with chronic coronary syndrome and high atherothrombotic risk on long-term oral anticoagulation, does the addition of aspirin improve...
Article
Evaluation of Optimal Duration of DAPT After PCI When Stratified by Bleeding Risk
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: What is the optimal duration of dual antiplatelet therapy (DAPT) after percutaneous coronary intervention (PCI) with drug-eluting stent (DES) placement...
Article
High-Normal Potassium Levels Reduce Ventricular Arrhythmias and Related Adverse Outcomes in High-Risk Patients with ICDs
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Does actively increasing serum potassium to the high-normal range (4.5 to 5.0 mmol/L) reduce malignant ventricular arrhythmias, arrhythmia-related...
Article
Acetylcholinesterase Inhibitors for Delirium Prevention: A Systematic Review and Meta-Analysis
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Do acetylcholinesterase inhibitors help reduce the occurrence and severity of delirium in hospitalized patients? Background: Delirium is a frequent...
Article
Beta-Blockers after Myocardial Infarction without Reduced Ejection Fraction
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Are beta-blockers beneficial in patients discharged after receiving invasive care for a myocardial infarction (MI) and with preserved left ventricular...
Article
Sodium Bicarbonate for Severe Metabolic Acidemia and Acute Kidney Injury: BICARICU-2
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Does sodium bicarbonate infusion in patients with moderate to severe acute kidney injury and severe metabolic acidosis reduce 90-day all-cause...
Article
Peripheral Vasopressors Safe in Early Sepsis Resuscitation
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Can vasopressors be safely administered through a peripheral line? Background: Traditionally, clinicians have administered vasopressors through central...
Article
Extended Low-Dose Apixaban After Provoked VTE Reduces Recurrence in Selected Patients
June 18, 2026
Mount Sinai Med-Lit Review Clinical question: Among patients with provoked venous thromboembolism (VTE) and ongoing risk factors, does extending anticoagulation with low-dose apixaban reduce...
Article
PrEP and PEP: What Hospitalists Need to Know
June 1, 2026
Although it may not always be top of mind for hospitalists, discussing or prescribing pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis (PEP) for human immunodeficiency virus (HIV) can...