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In pemphigus, phase 2 results with BTK inhibitor raise hopes for phase 3 trial
The well tolerated BTK inhibitor rilzabrutinib might be the first, but not last BTK inhibitor for pemphigus vulgaris. “The improvement...
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For diagnosing skin lesions, AI risks failing in skin of color
AI-aided diagnostic algorithms will not work in skin of color if machine training remains inadequate.
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Experts say teledermatology’s postpandemic role is unclear
There are many unknowns, not least of which is future reimbursement from the Centers for Medicare & Medicaid Services and other third-party...
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Topical anticholinergic for axillary hyperhidrosis shows fewer side effects
The agent, which shows strong activity at the application site but reduced systemic activity, is moving through the U.S. regulatory process.
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Systematic approach to pain helps avoid opioid issues for dermatologists
For most skin diseases, dermatologists should take the lead for pain management, but there are exceptions.
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In low-risk thyroid cancer, no advantage found for postsurgical iodine
Forgoing postoperative radioactive iodine in low-risk differentiated thyroid cancer is supported by phase 3 data.
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Denosumab now dominant therapy for osteoporosis linked to cancer
In changing patterns of osteoporosis drug prescriptions, denosumab has risen to the top of cancer indications.
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Obesity pegged as source of marked increased risk of diabetes in PCOS
Obesity has been identified as the key risk factor for type 2 diabetes in women with polycystic ovary syndrome in a new study. It suggests that...
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Success in achondroplasia spurs testing vosoritide in more growth disorders
The quality of growth achieved with vosoritide in achondroplasia is leading to studies in more growth disorders.
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Target-lesion failure reduced 2 years after MI with biodegradable stent
Two-year results from the BIOSTEMI trial shows advantage for biodegradable polymer stent in the setting of myocardial infarction.
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BASILICA technique prevents TAVR-related coronary obstruction in registry study
The largest ongoing BASILICA registry supports this procedure for TAVR-associated coronary obstruction.
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DOACs offered after heart valve surgery despite absence of data
Use of direct oral anticoagulants following heart valve surgery is occurring despite relative contraindications, but expert doubts its clinical...
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Cumulative exposure to high-potency topical steroid doses drives osteoporosis fractures
"A 3% increase in the relative risk of osteoporosis and MOF was observed per doubling of the TCS dose."