Dr. Kulkarni is an assistant professor of hospital medicine at Northwestern University in Chicago. She is editor of the Journal of Hospital Medicine POEMs.
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High-Dose Barium Enemas Prevent Recurrent Diverticular Bleeding
Clinical question Does barium impaction therapy using high-dose barium enemas prevent recurrent diverticular bleeding? Bottom line This small...
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Steroids May Benefit Patients With Severe CAP and High CRP Levels
Clinical question: Do steroids improve outcomes in patients with severe community-acquired pneumonia and a high inflammatory response? Bottom...
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2011 Resident Work Hour Reforms Had No Effect on Mortality or Readmissions
Clinical question Did the 2011 Accreditation Council for Graduate Medical Education resident work hour reforms affect patient outcomes? Bottom...
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Chlorhexidine Bathing Does Not Reduce Nosocomial Infections
Clinical question: For critically ill patients, does daily bathing with chlorhexidine reduce health care–associated infections? Bottom line...
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Procalcitonin-Based Algorithm Does Not Reduce Antibiotic Use in the ICU
Clinical question Can a procalcitonin-based algorithm reduce antibiotic use in critically ill patients? Bottom line A procalcitonin-based...
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Early Tube Feeding Does Not Improve Outcomes in Acute Pancreatitis
Clinical question Does early nasoenteric feeding decrease the rate of infections or death in patients hospitalized with severe acute...
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Intermittent PPI = Continuous-Infusion PPI for High-Risk Bleeding Ulcers
Clinical question Is intermittent proton pump inhibitor (PPI) therapy comparable with continuous-infusion PPI for the treatment of patients with...
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PEG Better and Faster than Lactulose for Initial Treatment of Hepatic Encephalopathy
Clinical question Is polyethylene glycol 3350-electrolyte solution an effective treatment for hospitalized patients with acute hepatic...
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No Survival Benefit With Early Goal-Directed Therapy for Septic Shock
Clinical question For patients presenting with early septic shock, does early goal-directed therapy reduce mortality? Bottom line As compared...
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Lower Transfusion Threshold for Sepsis Equals Fewer Transfusions, No Effect on Mortality
Clinical question Does a lower transfusion threshold for critically ill patients with septic shock affect outcomes? Bottom line Using a lower...
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New-Onset Perioperative Atrial Fibrillation Associated With Increased Risk of Ischemic Stroke
Clinical question For patients undergoing any inpatient surgery, is the presence of new-onset perioperative atrial fibrillation associated with a...
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Colchicine Prevents Postpericardiotomy Syndrome Following Cardiac Surgery
Clinical question Does perioperative colchicine reduce postpericardiotomy syndrome following cardiac surgery? Bottom line The use of colchicine...
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Shorter Stay, Fewer Interventions With Initial Cholecystectomy for Choledocholithiasis
Which strategy—initial cholecystectomy or common duct endoscopic investigation followed by cholecystectomy—leads to better outcomes in the...
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No Harm in Stopping Antibiotics After Cholecystectomy for Acute Cholecystitis
Does stopping antibiotic treatment after cholecystectomy for mild to moderate acute calculous cholecystitis affect outcomes?
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Questionable Benefit of Oral Chlorhexidine in Mechanically Ventilated Patients
For patients receiving mechanical ventilation, does routine oral care with chlorhexidine improve outcomes?