Mitchel is a reporter for MDedge based in the Philadelphia area. He started with the company in 1992, when it was International Medical News Group (IMNG), and has since covered a range of medical specialties. Mitchel trained as a virologist at Roswell Park Memorial Institute in Buffalo, and then worked briefly as a researcher at Boston Children's Hospital before pivoting to journalism as a AAAS Mass Media Fellow in 1980. His first reporting job was with Science Digest magazine, and from the mid-1980s to early-1990s he was a reporter with Medical World News. @mitchelzoler
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DAPA-HF: Dapagliflozin’s HFrEF efficacy confirmed in nondiabetics
PHILADELPHIA –
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FDA panel supports Vascepa expanded indication for CVD reduction
Icosapent ethyl (Vascepa), purified eicosapentaenoic acid, got unanimous support from an FDA panel for a new indication of reducing CVD events.
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ATTEST: AFib ablation slows progression to persistence
PARIS – AFib ablation cut the rate of paroxysmal to persistent arrhythmia progression by 89%, compared with medical management in a randomized...
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Bariatric surgery as safe in adolescents as it is in adults
Sleeve gastrectomy was significantly safer during the perioperative and immediate postoperative periods, compared with gastric bypass.
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Bariatric surgery shows metabolic benefits in lower-BMI patients
LAS VEGAS – Data from 45,000 patients showed that those who had a BMI below 35 kg/m2 benefited as much as those with higher BMIs.
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Previously healthy patients hospitalized for sepsis show increased mortality
WASHINGTON – U.S. patients hospitalized with community-acquired sepsis had higher mortality when they had no other comorbidities.
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Sacubitril/valsartan suggests HFpEF benefit in neutral PARAGON-HF
PARIS – PARAGON-HF’s primary endpoint was neutral, but desperation for a HFpEF therapy highlights a subgroup analysis.
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Flu vaccine cuts infection severity in kids and adults
Recent U.S. data compiled by the CDC documented that children and adults who received influenza vaccines had fewer severe infections.
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Birth year linked to influenza-subtype susceptibility
Analysis of a recent U.S. flu season showed some age groups were more prone to get H1N1 flu, while H3N2 predominated at other ages.
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FDA proposes new breast implant labeling with a boxed warning
Following a high-profile hearing in March 2019, and a textured breast implant recall in July, the FDA has proposed a boxed warning and other...
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Cell culture–based flu vaccine maintains immunogenicity
A 2018-2019 commercial flu vaccine made mostly by egg-free cell culture performed as well immunologically as standard vaccine.
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In utero Zika exposure can have delayed consequences
Infants born following in utero Zika virus exposure can appear normal at birth but have neurodevelopmental problems later.
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Valacyclovir safely cut vertical CMV transmission
A single-center, randomized study showed 8 g/day valacyclovir safely reduced CMV passage from mothers to their fetuses.
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Oral beta-lactams provide noninferior postdischarge pyelonephritis treatment
WASHINGTON – Beta-lactams were noninferior to fluoroquinolones or trimethoprim-...