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Length of Stay, Mortality Rise With Glycemic Variability
Major Finding: Length of stay increased by 6% and 90-day mortality by 9% for every 10 mg/dL increase in glucose standard deviation.
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Pancreas-Sparing GK Activator Lowers Glucose Without Hypoglycemia
Major Finding: At day 14, the percent reductions in 24-hour glucose profiles were 9% with 25 mg, 14% with 50 mg, 15% with 200 mg, 17% with 600 mg...
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Abatacept Delays Beta-Cell Loss in Type 1 Diabetes
Major Finding: At 36 months, the mean adjusted 2-hour C-peptide AUC was 0.215 nmol/L for the 64 abatacept patients in whom it was measured,...
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Tofacitinib Lowered Disease Activity in Ulcerative Colitis
Major Finding: The primary end point, clinical response at 8 weeks, occurred in 42% (20) of the patients who received placebo. The response was...
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Behavioral Problems Greater in Toddlers Who Snore
Major Finding: Overall Behavioral Symptoms Index (BSI) scores were 49.2 for the nonsnorers, 50.9 for the transient snorers, and 57.6 for the...
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Glargine, Liraglutide Neck and Neck, Except on Cost
Major Finding: Reductions in HbA1c from baseline did not differ significantly between the glargine and liraglutide groups (from 8.96% to 7.94% at...
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Glargine, Liraglutide Neck and Neck, Except on Cost
Major Finding: Reductions in HbA1c from baseline did not differ significantly between the glargine and liraglutide groups (from 8.96% to 7.94% at...
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Experimental Peptide Preserves Beta-Cells in Type 1 Diabetes
Major Finding: There was significant preservation of C-peptide levels, compared with placebo, with a relative change of 23% (P = .037) for all the...
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Admission HbA1c Aids Discharge Planning
Major Finding: In the postdischarge cohort, hemoglobin A1c dropped from 8.7% on admission to 7.3% at 12 weeks after discharge.
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HIV Incidence Higher in Young Black MSM Community
Major Finding: After 1 year of follow-up, among the 1,009 black MSM who had at least one follow-up test at 6 months or 1 year, the overall...
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Adult Immunization Program Needs Shot in the Arm
Major Finding: Compared with 2009 NHIS estimates, only modest increases in adult use were seen in 2010 for the Tdap vaccination (1.6% rise, to 8.2...
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Genetic Screening Targets Maturity-Onset Diabetes of Youth
Major Finding: The screening policy added 0.01 quality-adjusted life years (19.22 vs. 19.21 with no screening). Data Source: The study simulated...