Oral step-down therapy for infective endocarditis
December 13, 2021
What is oral step-down therapy’s relative clinical effectiveness, compared with prolonged IV antibiotics for infective endocarditis (IE)?
Anticoagulant choice in antiphospholipid syndrome–associated thrombosis
December 10, 2021
Are direct oral anticoagulants (DOACs) as efficacious and safe as vitamin K antagonists (VKAs) in treating thrombosis secondary to antiphospholipid syndrome (APS)?
Timing of initiation of renal-replacement therapy in acute kidney injury
December 8, 2021
In critically ill patients, does early renal-replacement therapy (RRT), compared with standard therapy, improve death from any cause at 90 days?
Prophylactic haloperidol does not improve survival in critically ill patients
August 9, 2018
Does prophylactic use of haloperidol in critically ill patients at high risk of delirium improve survival at 28 days?
Multifaceted pharmacist intervention may reduce postdischarge ED visits and readmissions
August 2, 2018
Can a multifaceted intervention by a clinical pharmacist reduce the rate of ED visits and readmission over the subsequent 180 days?
Balanced fluid resuscitation vs. saline does not decrease hospital-free days
August 1, 2018
Does balanced crystalloid fluid improve outcomes versus saline in noncritically ill patients who are hospitalized?
Myeloproliferative neoplasms increase risk for arterial and venous thrombosis
July 2, 2018
What are the risks for arterial and venous thrombosis in patients with myeloproliferative neoplasms (MPNs)?
Steroids do not reduce mortality in patients with septic shock
June 27, 2018
Among patients with septic shock undergoing mechanical ventilation, does hydrocortisone reduce 90-day mortality?
Prompting during rounds decreases lab utilization in patients nearing discharge
June 26, 2018
Does prompting hospitalists during interdisciplinary rounds to discontinue lab orders on patients nearing discharge result in a decrease in lab testing?
The hospitalist as intensivist
May 21, 2018
What roles, training, and support do hospitalists have and perceive in the intensive care unit?